4-Nitro-D-phenylalanine hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 147065-06-3 |
| Product name | 4-Nitro-D-phenylalanine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Nitro-D-phenylalanine hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Nitro-D-phenylalanine hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Nitro-D-phenylalanine hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral building block for constructing drug molecules containing nitrophenylalanine structures | Intermediate in multi-step organic synthesis, used in peptide chain elongation or functional group transformations |
| Biochemical Research | Study of enzyme specificity and catalytic mechanisms toward aromatic amino acid derivatives | Used as substrate or inhibitor in enzyme kinetic assays |
| Medicinal Chemistry | Structural unit in prodrug design or targeted delivery systems | Incorporated into drug molecule scaffolds via amidation, esterification, and related reactions |
| Diagnostics Reagent Development | Synthetic precursor for fluorescent or radio-labeled probes | Coupled with labeling moieties for use in bioimaging or analytical detection |
Manufacturing Quality Control of 4-Nitro-D-phenylalanine hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient reversed-phase HPLC with UV detection; reported as area percent relative to main peak. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents based on retention time and peak area calibration. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent where water reacts stoichiometrically with iodine and sulfur dioxide in pyridine/methanol medium. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using mass spectrometry for high sensitivity and specificity. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using a silver indicator electrode; endpoint detected by abrupt potential change due to AgCl precipitation. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity and enantiomeric purity. |
| Residue on Ignition | Gravimetric Analysis | Heating sample at 700-800 C to constant weight; residue represents non-volatile inorganic impurities expressed as percentage of initial mass. |
| pH (1% w/v aqueous solution) | pH Meter | Electrochemical measurement of hydrogen ion activity in a freshly prepared aqueous solution using calibrated glass electrode. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity versus angle to determine volume-based particle size distribution in dispersed solid sample. |
| Microbial Limits | Membrane Filtration | Filtration of sample solution followed by culture on selective media; enumeration of aerobic bacteria, yeasts, and molds per pharmacopeial limits. |
| Melting Point | Capillary Melting Point Apparatus | Thermal determination of temperature range at which solid transitions to liquid, indicating crystallinity and absence of significant eutectic impurities. |
Technical Specifications of 4-Nitro-D-phenylalanine hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 215–219 °C |
| Optical Rotation | -20.0 to -24.0 ° (c=1, 6M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Nitro-D-phenylalanine hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Nitro-D-phenylalanine hydrochloride
Safety Information of 4-Nitro-D-phenylalanine hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Nitro-D-phenylalanine hydrochloride
Industrial 4-Nitro-D-phenylalanine hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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