4-Bromo-2-fluorobenzylamine hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 147181-08-6 |
| Product name | 4-Bromo-2-fluorobenzylamine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Bromo-2-fluorobenzylamine hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Bromo-2-fluorobenzylamine hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Bromo-2-fluorobenzylamine hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing antitumor agents and protein kinase inhibitors | Prepared via salt formation between 4-bromo-2-fluorobenzylamine and hydrochloric acid; used in subsequent coupling or acylation reactions to construct drug molecule scaffolds |
| Pesticides | Intermediate for synthesizing novel fluorinated fungicides or insecticides | Serves as a fluorinated aromatic amine component in nucleophilic substitution or reductive amination reactions to introduce fluorophenyl moieties |
| Chemical Reagents | Organic building block for constructing bromo-fluoroaniline structures in research | Functions as a functionalized aromatic amine, serving as the amine source in cross-coupling reactions (e.g., Suzuki, Buchwald–Hartwig) |
Manufacturing Quality Control of 4-Bromo-2-fluorobenzylamine hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~220–254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV/DAD | Separation and identification of impurities (e.g., starting materials, isomers, dehalogenated by-products) using gradient HPLC with diode-array detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., methanol, acetone, DMF) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with sample moisture. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, offering sub-pptr detection limits. |
| Chloride Ion Impurity | Potentiometric Titration (AgNO₃) | Titration with silver nitrate using a silver indicator electrode; endpoint detected by abrupt potential change due to AgCl precipitation. |
| Residue on Ignition | Gravimetric Analysis | Incineration at 600–700 °C followed by weighing of inorganic residue to assess inorganic ash content. |
| Optical Rotation | [α]D Measurement | Polarimetric measurement at 589 nm (Na D-line) to confirm chiral integrity and absence of racemization during synthesis/handling. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using Mie scattering theory to determine D10, D50, D90 values per USP <429>. |
| pH of Aqueous Solution | pH Potentiometry | Measurement using calibrated glass electrode in a saturated aqueous suspension (10 mg/mL) to assess acidity from residual HCl and hydrolytic stability. |
| Melting Point | Capillary Melting Point Apparatus | Thermal analysis to verify identity and purity based on sharpness and agreement with literature value (~175–178 °C). |
Technical Specifications of 4-Bromo-2-fluorobenzylamine hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 142-146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Bromo-2-fluorobenzylamine hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Bromo-2-fluorobenzylamine hydrochloride
Safety Information of 4-Bromo-2-fluorobenzylamine hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Bromo-2-fluorobenzylamine hydrochloride
Industrial 4-Bromo-2-fluorobenzylamine hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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