China Factory Direct
|
|
| CAS number | 14719-37-0 |
| Product name | TERT-BUTOXYCARBONYLAMINO-ACETIC ACID ETHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of amino acid–based drugs; used in the preparation of peptide therapeutics and antibiotics | Introduces glycine structure via Boc protection in organic synthesis, followed by deprotection and coupling reactions |
| Biochemistry | Building block for glycine residues in peptide synthesis | Participates in condensation reactions as a monomer using solid-phase or solution-phase peptide synthesis techniques |
| Polymer Materials | Precursor in the synthesis of functionalized polymers | Participates in graft polymerization or crosslinking reactions via ester or amino functional groups |
| Chemical Reagents | Standard chemical for laboratory research and analytical applications | Used in the synthesis of other nitrogen-containing compounds or as a reaction intermediate for mechanistic studies |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~210 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities (e.g., N-BOC-glycine, glycine ethyl ester, di-BOC derivatives) using gradient HPLC with UV detection. |
| Residual Solvents (e.g., EtOH, THF, DCM) | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification of trace metals after acid digestion, leveraging high sensitivity and isotopic resolution. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation of chloride ions on an anion-exchange column and quantitative detection via suppressed conductivity. |
| Residual BOC Anhydride | GC-FID or HPLC-UV | Direct quantification of di-tert-butyl dicarbonate by GC-FID or its hydrolysis product (tert-butanol) by HPLC-UV. |
| Optical Rotation | [α]D | Measurement of specific rotation at 589 nm using a polarimeter to confirm chiral integrity (though compound is achiral; used to detect chiral contaminants). |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination via controlled heating; used for identity and purity assessment (sharp range indicates high purity). |
| pH of Aqueous Solution (1% w/v) | pH Meter | Potentiometric measurement indicating residual acidic/basic impurities affecting protonation state. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Analysis | Weighing inorganic residue after high-temperature incineration with sulfuric acid treatment, per USP <281>. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow liquid |
| Purity | >=98.5% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic ester-like odor |
| Solubility | Soluble in common organic solvents (e.g., methanol, dichloromethane, ethyl acetate) |
|
|
|
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.