5-Bromo-1,3-difluoro-2-nitrobenzene Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 147808-42-2 |
| Product name | 5-Bromo-1,3-difluoro-2-nitrobenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 5-Bromo-1,3-difluoro-2-nitrobenzene
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 5-Bromo-1,3-difluoro-2-nitrobenzene Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 5-Bromo-1,3-difluoro-2-nitrobenzene
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of novel fluorinated insecticide intermediates | Bromine and nitro groups are introduced via electrophilic substitution, followed by fluorination |
| Pharmaceuticals | Synthesis of intermediates for anticancer agents and antibiotics | Used as an aromatic ring building block in multi-step condensation and coupling reactions |
| Polymers | Functional monomer for fluorinated polymer synthesis | Incorporated into polymer chains via palladium-catalyzed coupling reactions (e.g., Suzuki, Stille) |
| Fine Chemicals | Production of fluorinated dyes and photochromic materials | Nitro group is reduced to amino, followed by azo coupling or diazotization |
| Organic Synthesis | General intermediate for pharmaceuticals and agrochemicals | Used as a starting material; complex molecular frameworks are constructed through nitro reduction, halogen exchange, and related transformations |
Manufacturing Quality Control of 5-Bromo-1,3-difluoro-2-nitrobenzene
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 254 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time relative to reference standards. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection for quantification of common organic solvents (e.g., dichloromethane, toluene) per ICH Q3C. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content in the sample. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, with detection limits <1 ppb. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated digital apparatus per USP <741>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and presence of visible particulates under controlled white light against standard reference. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing at 700-800 C, expressed as % w/w. |
| Organic Volatile Impurities (OVI) | GC-FID | Screening for unspecified volatile organics by static headspace GC-FID with internal standard calibration. |
| Bulk Density | Tap Density Tester | Measurement of mass per unit volume after standardized tapping per USP <616>. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder size distribution using Mie scattering theory with air dispersion. |
Technical Specifications of 5-Bromo-1,3-difluoro-2-nitrobenzene
| Test Item | Specification |
|---|---|
| Appearance | Gray-green solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 68–72°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 5-Bromo-1,3-difluoro-2-nitrobenzene
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 5-Bromo-1,3-difluoro-2-nitrobenzene
Safety Information of 5-Bromo-1,3-difluoro-2-nitrobenzene
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 5-Bromo-1,3-difluoro-2-nitrobenzene
Industrial 5-Bromo-1,3-difluoro-2-nitrobenzene Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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