China Factory Direct
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| CAS number | 1480-64-4 |
| Product name | 3-Chloro-2-fluoro-pyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Agricultural Chemicals | Intermediate for synthesizing herbicides, insecticides, and other agrochemicals | Serves as a key structural unit in constructing heterocyclic compounds, applied in synthesizing aryl oxyphenoxypropionic acid herbicides such as fluazifop |
| Pharmaceuticals | Intermediate for preparing active pharmaceutical ingredients (APIs) | Applied in synthesizing fluorinated pyridine-containing drug candidates, commonly used in oncology, antiviral, and central nervous system drug development |
| Chemical Synthesis | Organic synthesis building block | Introduces chloro- or fluoro-pyridyl scaffolds into target molecules via nucleophilic substitution or transition-metal-catalyzed coupling reactions (e.g., Suzuki, Buchwald–Hartwig) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detector | Quantifies main component by retention time and peak area against calibrated standard. |
| Related Substances | Gas Chromatography-Mass Spectrometry (GC-MS) | Identifies and semi-quantifies impurities based on retention time and mass spectral fragmentation patterns. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Measures volatile organic solvents by equilibrium partitioning into headspace followed by GC separation. |
| Water Content | Karl Fischer Titration | Determines water via stoichiometric reaction between water, iodine, sulfur dioxide, and base in methanol medium. |
| Chloride Content | Ion Chromatography (IC) | Separates and quantifies chloride anions using ion-exchange column and conductivity detection. |
| Fluoride Content | Ion-Selective Electrode (ISE) | Measures free fluoride ion activity in solution via potentiometric response of lanthanum fluoride crystal membrane. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma-Optical Emission Spectrometry (ICP-OES) | Quantifies trace metals by atomization and excitation in high-temperature plasma, detecting element-specific emission lines. |
| Acidity (as HCl) | Acid-Base Titration with NaOH | Neutralizes acidic impurities using standardized sodium hydroxide solution and phenolphthalein endpoint. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after controlled high-temperature ashing and weighing. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity against specified standards under controlled lighting. |
| Melting Point | Capillary Melting Point Determination | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus. |
| Specific Optical Rotation | Polarimetry | Measures rotation of plane-polarized light caused by chiral impurities or enantiomeric excess in solution. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to pale yellow liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Refractive Index (n20/D) | 1.505–1.515 |
| Relative Density (20°C/25°C) | 1.32–1.34 g/cm³ |
| Odor | Characteristic aromatic odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.