2,4-Difluoro-5-chloronitrobenzene Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1481-68-1 |
| Product name | 2,4-Difluoro-5-chloronitrobenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,4-Difluoro-5-chloronitrobenzene
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,4-Difluoro-5-chloronitrobenzene Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,4-Difluoro-5-chloronitrobenzene
| Industry | Application | Process |
|---|---|---|
| Pesticide Manufacturing | Key intermediate in the synthesis of sulfluramid | Multi-step organic synthesis involving nitration, chlorination, and fluorination; typically prepared via selective chlorination of 2,4-difluoronitrobenzene |
| Pharmaceutical R&D | Building block for fluorinated nitroaromatic scaffolds in drug candidates, including antitumor and antimicrobial compounds | Serves as an aromatic substitution module in medicinal chemistry modifications, including nucleophilic aromatic substitution and palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) |
| Materials Science | Structural unit in liquid crystal monomers and organic optoelectronic materials, enhancing molecular polarity and thermal stability | Functionalized via reduction of the nitro group to amino followed by diazotization and coupling, or directly incorporated into fluorinated aryl ring functionalization polymerization reactions |
Manufacturing Quality Control of 2,4-Difluoro-5-chloronitrobenzene
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Gas Chromatography (GC) with FID detection | Quantitative determination based on peak area comparison against a certified reference standard using a non-polar capillary column. |
| Related Substances | Gas Chromatography (GC) with FID or MS detection | Separation and quantification of structurally related impurities (e.g., isomers, residual starting materials, by-products) relative to main peak. |
| Residual Solvents | Gas Chromatography (GC) with Headspace sampling | Volatile organic solvents (e.g., dichloromethane, toluene) are quantified via headspace equilibrium and flame ionization detection. |
| Water Content | Karl Fischer Titration (Coulometric mode) | Electrochemical titration where iodine generated in situ reacts stoichiometrically with water; measures trace moisture in solid samples. |
| Chloride Ion Impurity | Ion Chromatography (IC) with conductivity detection | Separation of anions on an ion-exchange column followed by quantitative detection of chloride via suppressed conductivity. |
| Heavy Metals (as Pb) | Inductively Coupled Plasma Optical Emission Spectrometry (ICP-OES) | Multi-element elemental analysis after acid digestion; detection based on characteristic atomic emission lines. |
| Acid-Neutralizable Impurities | Acid-Base Titration (NaOH standard solution) | Titration of acidic impurities (e.g., HCl, nitrophenols) with standardized sodium hydroxide using phenolphthalein indicator. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed as solid-to-liquid phase change; used for identity confirmation and purity estimation. |
| Appearance | Visual Inspection (against white/black background) | Assessment of physical state, color, and presence of particulates or discoloration in the neat solid sample. |
| Loss on Drying (LOD) | Gravimetric Analysis (105 C, 2 h) | Mass loss measured after drying under controlled temperature and time; reflects volatile content including residual solvents and moisture. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light by chiral contaminants (if applicable); confirms absence of optically active impurities. |
| Residue on Ignition | Gravimetric Sulfated Ash Test | Mass of non-volatile inorganic residue remaining after high-temperature ignition (700–800 C) following sulfuric acid treatment. |
Technical Specifications of 2,4-Difluoro-5-chloronitrobenzene
| Test Item | Specification |
|---|---|
| Appearance | Yellow liquid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | -15 to -10°C |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,4-Difluoro-5-chloronitrobenzene
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,4-Difluoro-5-chloronitrobenzene
Safety Information of 2,4-Difluoro-5-chloronitrobenzene
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 2,4-Difluoro-5-chloronitrobenzene
Industrial 2,4-Difluoro-5-chloronitrobenzene Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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