China Factory Direct
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| CAS number | 148101-51-3 |
| Product name | AC-LYS(FMOC)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Protected amino acid monomer for peptide synthesis | Solid-phase peptide synthesis (SPPS) for constructing peptide chains containing lysine residues, with the α-amino group acetyl-protected and the side-chain ε-amino group FMOC (9-fluorenylmethyloxycarbonyl)-protected to enable selective deprotection and coupling |
| Chemical Research | Organic synthesis intermediate | Used to prepare lysine derivatives with specific functional group modifications for constructing complex molecular architectures or probe molecules |
| Pharmaceutical Development | Structural building block for targeted therapeutics or prodrugs | Employed as a linker or functionalized amino acid component in novel therapeutic molecules, including protein degraders (e.g., PROTACs) and antibody-drug conjugates (ADCs) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 265 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Separation and detection of impurities using gradient HPLC-UV; identification and quantification based on relative retention times and response factors. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common solvents (e.g., DMF, DCM, methanol) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content by electrochemical endpoint detection. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Heavy Metals | ICP-MS | Quantitative determination of elemental impurities (e.g., Pb, Cd, Ni, Cu) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Residual Palladium | ICP-MS | Specific quantification of Pd residues from coupling catalysts via acid digestion followed by ICP-MS analysis with isotope dilution. |
| Chloride Content | Ion Chromatography | Separation and conductivity detection of chloride ions in aqueous extract using anion-exchange column and suppressed conductivity detection. |
| Loss on Drying | Gravimetric Analysis | Weight loss measured after drying under controlled temperature and vacuum, indicating volatile content including residual solvents and moisture. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using laser diffraction to determine volume-based particle size distribution (D10, D50, D90). |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) using membrane filtration and selective agar culture. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of pH in a 1% w/v aqueous suspension using calibrated glass electrode and pH meter. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128-132°C |
| Optical Rotation | +18.5° to +20.5° (c=1, in DMF) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.