China Factory Direct
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| CAS number | 148249-36-9 |
| Product name | 3-BROMO-1-(TRIISOPROPYLSILYL)INDOLE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Organic synthesis intermediate for constructing indole-containing drug molecules | Triisopropylsilyl-protected indole scaffold introduced via Suzuki coupling, Buchwald–Hartwig amination, or nucleophilic substitution |
| Agrochemicals | Lead compound for synthesizing novel insecticides or fungicides | Used as precursor to functionalized indole derivatives, undergoing structural modification under transition-metal catalysis |
| Materials Science | Used in synthesizing functionalized organic semiconductors or fluorescent materials | Conjugated systems constructed via coupling reactions; triisopropylsilyl group serves as a steric protecting group to modulate molecular packing |
| Chemical Research | Intermediate in protecting-group strategies for total synthesis of complex natural products | Indole N–H site protected during multistep synthesis; deprotection enables selective functionalization |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main compound by UV absorption at specific wavelength using reverse-phase chromatography with calibrated standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, toluene) by gas chromatographic separation and flame ionization detection. |
| Moisture Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration based on iodine-sulfur dioxide redox reaction. |
| Heavy Metals | ICP-OES | Quantifies elemental impurities (e.g., Pb, Cd, Ni) after acid digestion using plasma excitation and optical emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column and conductivity detection. |
| Residual Catalyst (Pd) | ICP-MS | Detects trace palladium from cross-coupling reactions using inductively coupled plasma mass spectrometry. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using controlled heating and visual observation. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation of chiral compounds using sodium D-line light in a polarimeter. |
| Residue on Ignition | Gravimetric Analysis | Quantifies non-volatile inorganic residue after high-temperature ashing and weighing. |
| Appearance | Visual Inspection | Assesses physical state, color, and presence of particulates or discoloration against established reference standards. |
| pH of Solution | pH Meter | Measures hydrogen ion activity in aqueous suspension or solution using calibrated glass electrode. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112-116°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.