China Factory Direct
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| CAS number | 148644-09-1 |
| Product name | 3-Methoxyazetidine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Industry | Key intermediate in the synthesis of the antibiotic drug tazobactam | Condensation with a specific thiazole ring precursor to construct the diazabicyclooctane scaffold |
| Pharmaceutical Industry | Co-crystal former for improving the physicochemical properties of active pharmaceutical ingredients (APIs) | Co-crystal preparation via supramolecular synthesis to enhance API solubility or stability |
| Pharmaceutical Industry | Nitrogen-containing heterocyclic building block for synthesizing novel small-molecule drug screening libraries | Combinatorial chemistry or medicinal chemistry scaffold hopping, leveraging ring strain for ring-opening or structural modification |
| Organic Synthesis | Nucleophile or ligand in catalytic organic synthesis reactions | Transition-metal-catalyzed reactions (e.g., palladium-catalyzed coupling) or nucleophilic substitution reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3A/B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction with water. |
| Chloride Content | Ion Chromatography (IC) | Quantitative separation and detection of chloride ions using anion-exchange column and conductivity detection, referenced to sodium chloride standard. |
| Heavy Metals | ICP-OES | Multi-element detection after acid digestion using inductively coupled plasma optical emission spectrometry; total heavy metals reported as Pb equivalent. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after controlled ashing at 700-800 C, expressed as percentage weight loss. |
| Optical Rotation | [alpha]D Measurement | Determination of specific optical rotation using a digital polarimeter at 20 C with sodium D-line (589 nm), indicating enantiomeric purity. |
| pH (1% w/v aqueous solution) | pH Potentiometry | Measurement of hydrogen ion activity in aqueous solution using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using laser scattering to determine volume-based particle size distribution (D10, D50, D90). |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity of solid material against established reference standard under controlled lighting conditions. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 145–149 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.