Methyl N-Boc-piperidine-3-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 148763-41-1 |
| Product name | Methyl N-Boc-piperidine-3-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Methyl N-Boc-piperidine-3-carboxylate
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Methyl N-Boc-piperidine-3-carboxylate Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Methyl N-Boc-piperidine-3-carboxylate
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used as a key intermediate in synthesizing piperidine-containing drug molecules, including antipsychotics, antidepressants, and analgesics | Integrated into multi-step organic syntheses to construct target compound scaffolds via deprotection (e.g., Boc removal), ester hydrolysis, or amine functional group transformations |
| Agricultural Chemicals | Applied in synthesizing biologically active nitrogen-containing heterocyclic pesticides or plant growth regulators | Employed as a structural module for heterocycle modification and side-chain introduction to enhance target selectivity and biological activity |
| Chemical Reagents | Utilized to build compound libraries featuring 3-substituted piperidine motifs, supporting high-throughput screening and structure–activity relationship (SAR) studies | Used as a building block in solid-phase or solution-phase synthesis, incorporating complex structures via palladium-catalyzed coupling, reductive amination, and related reactions |
Manufacturing Quality Control of Methyl N-Boc-piperidine-3-carboxylate
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies impurities by gradient HPLC-UV, with identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., methanol, toluene) using gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generated electrochemically in pyridine-free reagent. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation using a digital polarimeter at 20 C and sodium D-line (589 nm) to confirm chiral integrity. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni) after acid digestion using inductively coupled plasma mass spectrometry with isotope dilution. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using anion-exchange column with suppressed conductivity detection. |
| Residual Palladium | ICP-OES | Determines palladium residue from catalytic hydrogenation using inductively coupled plasma optical emission spectroscopy. |
| Acid Value | Acid-Base Titration | Measures free carboxylic acid groups by titration with standardized NaOH solution using phenolphthalein indicator. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of sample against water-white standard under controlled white light and specified viewing conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Particle Size Distribution | Laser Diffraction | Measures particle size distribution in dry powder form using laser scattering principle and Mie theory-based analysis. |
Technical Specifications of Methyl N-Boc-piperidine-3-carboxylate
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow semi-solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Optical Rotation | -15.0° to -19.0° (c=1, CHCl3) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Methyl N-Boc-piperidine-3-carboxylate
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Methyl N-Boc-piperidine-3-carboxylate
Safety Information of Methyl N-Boc-piperidine-3-carboxylate
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of Methyl N-Boc-piperidine-3-carboxylate
Industrial Methyl N-Boc-piperidine-3-carboxylate Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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