DL-Pyroglutamic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 149-87-1 |
| Product name | DL-Pyroglutamic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradePharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for DL-Pyroglutamic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk DL-Pyroglutamic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of DL-Pyroglutamic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of amino acid-based drugs, e.g., for preparing glutamic acid and arginine | Decarboxylation or reduction of DL-pyroglutamic acid as a precursor via chemical synthesis |
| Food Additives | Flavor enhancer (umami enhancer) to improve savory taste | Incorporated into food processing via enzymatic or chemical methods, acting synergistically with nucleotides |
| Cosmetics | Humectant and skin-conditioning agent to improve skin feel | Added as a functional ingredient in emulsions, creams, and similar formulations, leveraging its hydrophilicity |
| Biotechnology | Component of cell culture media to support cell growth | Supplemented as a nitrogen source, providing bioavailable amino acid precursors during microbial fermentation |
| Agriculture | Plant nutrient additive to promote crop growth | Applied via foliar spray or soil application to enhance plant nitrogen uptake efficiency |
Manufacturing Quality Control of DL-Pyroglutamic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration with NaOH | Quantifies DL-pyroglutamic acid by neutralization with standardized sodium hydroxide solution using phenolphthalein or potentiometric endpoint detection. |
| Specific Optical Rotation | [α]D | Measures optical rotation of a solution at 20 °C using sodium D-line (589 nm) to confirm chiral integrity and absence of significant enantiomeric excess. |
| Loss on Drying (LOD) | Gravimetric Thermogravimetry (105 °C, 2 h) | Determines volatile content (e.g., residual water/solvents) by mass loss upon controlled heating under standard conditions. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Sulfated Ash Test | Measures inorganic impurities by incineration of sample with sulfuric acid followed by high-temperature ashing and weighing of residual inorganic salts. |
| Heavy Metals (as Pb) | ICP-OES or AAS after Acid Digestion | Quantifies total heavy metals (expressed as lead) via atomic emission or absorption spectroscopy following microwave-assisted nitric/hydrochloric acid digestion. |
| Chloride Impurity | Potentiometric Titration with AgNO₃ | Determines chloride ions by argentometric titration using silver nitrate and a silver indicator electrode or potentiometric endpoint. |
| Sulfate Impurity | Turbidimetric Analysis (BaCl₂ method) | Measures sulfate as insoluble barium sulfate precipitate; quantified by light scattering intensity relative to standard calibration curve. |
| Related Substances (Impurity Profile) | HPLC-UV (C18 column, acidic mobile phase) | Separates and quantifies structurally related impurities (e.g., glutamic acid, pyroglutamic acid isomers, degradation products) using reversed-phase chromatography with UV detection at 210 nm. |
| Water Content | Karl Fischer Coulometric Titration | Determines trace water content based on stoichiometric electrochemical iodine generation and reaction with water in anhydrous methanol/pyridine medium. |
| pH (1% aqueous solution) | Potentiometric pH Measurement | Measures hydrogen ion activity in a standardized 10 mg/mL aqueous solution using calibrated glass electrode system at 25 °C. |
| Microbial Limits | Membrane Filtration / Plate Count | Assesses aerobic microbial contamination per pharmacopeial (e.g., USP <61>) or industrial specifications using filtration and cultivation on soybean-casein digest agar. |
| Particle Size Distribution | Laser Diffraction (Dry Dispersion) | Determines volumetric particle size distribution (D10, D50, D90) by analyzing angular scattering pattern of laser light passed through dispersed powder. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid phase transition using calibrated digital melting point instrument per USP <741>. |
Technical Specifications of DL-Pyroglutamic acid
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 71.0–73.0°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of DL-Pyroglutamic acid
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| Lot/Batch Number | *Required fields | |
NMR Spectra of DL-Pyroglutamic acid
Packaging of DL-Pyroglutamic acid
Industrial DL-Pyroglutamic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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