D-Tryptophan methyl ester hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 14907-27-8 |
| Product name | D-Tryptophan methyl ester hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D-Tryptophan methyl ester hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D-Tryptophan methyl ester hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D-Tryptophan methyl ester hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral intermediates for synthesizing anticancer agents (e.g., peptide-based drugs) and 5-HT receptor modulators | Used as chiral building blocks in solid-phase or solution-phase peptide coupling reactions, followed by deprotection and hydrolysis to construct active molecules |
| Pharmaceuticals | Impurity reference standards and quality control reference materials for L-DOPA–based drugs | Applied as chemical reference standards in HPLC and LC-MS analyses for chromatographic retention time and response calibration |
| Biochemical Research | Substrate for enzyme kinetics studies, used in specific activity assays of tryptophanase, arylalkanoic acid dehydrogenase, and similar enzymes | Employed as a specific enzymatic substrate in buffered systems (e.g., Tris-HCl, pH 7.5–8.5) to monitor product formation rates |
| Food & Feed | Potential nutrient fortificant component (under research; not approved by major regulatory authorities) | Exploratory laboratory-scale addition to animal feed to assess effects on tryptophan metabolism and growth performance (non-commercial application) |
Manufacturing Quality Control of D-Tryptophan methyl ester hydrochloride
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies D-tryptophan methyl ester hydrochloride by reversed-phase HPLC with UV detection at 280 nm, using a calibrated standard reference. |
| Chiral Purity | Chiral HPLC | Separates D- and L-enantiomers on a chiral stationary phase; enantiomeric excess is calculated from peak area ratios. |
| Water Content | Karl Fischer Titration | Measures water via coulometric or volumetric titration with iodine, based on the stoichiometric reaction of water with iodine and sulfur dioxide in pyridine/methanol medium. |
| Residual Solvents | GC-FID | Detects and quantifies residual methanol, ethyl acetate, or dichloromethane using gas chromatography with flame ionization detection against certified standards. |
| Heavy Metals | ICP-OES | Determines total heavy metals (e.g., Pb, Cd, Ni, Fe) after acid digestion by measuring elemental emission intensities at characteristic wavelengths. |
| Chloride Content | Potentiometric Titration | Titrates chloride ions with silver nitrate using a silver indicator electrode; endpoint detected by potential change. |
| pH of Aqueous Solution | pH Potentiometry | Measures hydrogen ion activity in a 1% w/v aqueous solution using a calibrated glass electrode pH meter. |
| Specific Optical Rotation | [a]D Measurement | Determines optical rotation at 589 nm (Na-D line) using a polarimeter; value confirms chiral identity and batch consistency. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., D-tryptophan, methyl ester hydrolysis products) using gradient HPLC with UV detection. |
| Loss on Drying | Gravimetric Analysis | Measures weight loss after drying under controlled temperature and vacuum; reflects volatile content and residual solvents. |
| Appearance | Visual Inspection | Assesses physical form, color, and homogeneity against established reference standards under controlled lighting. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic mesophilic microorganisms and detects specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial procedures. |
Technical Specifications of D-Tryptophan methyl ester hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 215–220 °C |
| Optical Rotation | -22 to -17 deg (c=1, H2O) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D-Tryptophan methyl ester hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D-Tryptophan methyl ester hydrochloride
Safety Information of D-Tryptophan methyl ester hydrochloride
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of D-Tryptophan methyl ester hydrochloride
Industrial D-Tryptophan methyl ester hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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