(3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 149198-47-0 |
| Product name | (3R,4S)-tert-Butyl 2-oxo-4-phenyl-3-(triethylsilyloxy)azetidine-1-carboxylate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 149198-47-0
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 149198-47-0 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 149198-47-0
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate in the synthesis of antiviral drugs | Key step for constructing azetidinone derivatives |
| Pharmaceutical R&D | Development of novel protease inhibitors | Synthesis and application of chiral ligands or catalysts |
| Fine Chemicals | Preparation of high-purity chiral compounds | Introduction and selective removal of silyl protecting groups |
| Organic Synthesis | Used as a chiral auxiliary or chiral building block | Silyloxy-based protection strategy in highly stereoselective reactions |
Manufacturing Quality Control of 149198-47-0
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 210-230 nm, comparing peak area to reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC with UV detection and relative response factors. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, toluene, ethyl acetate) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines water content via coulometric or volumetric titration using iodine generation in pyridine-free reagent. |
| Heavy Metals | ICP-MS | Quantifies trace metals (Pb, Cd, Hg, As, Ni, etc.) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chiral Purity | Chiral HPLC-UV | Evaluates enantiomeric excess by separation on chiral stationary phase with UV detection, comparing retention times and peak areas. |
| Residual Catalyst (Pd) | ICP-OES | Measures palladium residue after microwave-assisted acid digestion using inductively coupled plasma optical emission spectrometry. |
| Residual Triethylamine | GC-FID | Quantifies triethylamine by headspace or direct injection GC with FID detection using external calibration. |
| Acid Value | Acid-Base Titration | Determines free carboxylic acid groups via titration with standardized NaOH solution using phenolphthalein or potentiometric endpoint. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of solid sample against established visual standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range at which solid transitions to liquid using calibrated capillary apparatus per USP <741>. |
| Residual TESCl | GC-MS | Identifies and quantifies residual triethylsilyl chloride by gas chromatography coupled with mass spectrometric detection. |
Technical Specifications of 149198-47-0
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Optical Rotation | [α]²⁰D = -15.0° to -19.0° (c=1.0, CHCl₃) |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 149198-47-0
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 149198-47-0
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Industrial 149198-47-0 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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