2-Boc-aminomethylpyrrolidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 149649-58-1 |
| Product name | 2-Boc-aminomethylpyrrolidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25L/drum |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2-Boc-aminomethylpyrrolidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2-Boc-aminomethylpyrrolidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2-Boc-aminomethylpyrrolidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as an intermediate in the synthesis of pharmaceuticals (e.g., antidepressants, antivirals) | Organic synthesis, chiral resolution |
| Biochemistry | Applied in peptide synthesis and protein structural modification | Solid-phase synthesis, liquid-phase synthesis |
| Materials Science | Employed to prepare functionalized polymeric materials or catalyst ligands | Polymerization, coordination chemistry |
| Academic Research | Utilized as a reagent to investigate reaction mechanisms or biological activity of pyrrolidine derivatives | Experimental analysis, structural characterization |
Manufacturing Quality Control of 2-Boc-aminomethylpyrrolidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~210 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-UV | Separation and quantification of structurally related impurities (e.g., de-Boc product, regioisomers, residual starting materials) using gradient elution and UV detection. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., THF, DMF, ethyl acetate, methanol) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS | Quantitative multi-element analysis of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, offering sub-ppt detection limits per ICH Q3D. |
| Residual Palladium | ICP-MS or ICP-OES | Specific quantification of Pd catalyst residues (if used in synthesis) following microwave-assisted acid digestion and elemental detection. |
| Optical Rotation | [α]D Measurement | Determination of specific optical rotation using a polarimeter at 589 nm (Na D-line) to confirm chiral integrity and enantiomeric identity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement by observing solid-to-liquid phase change under controlled heating rate; verifies crystallinity and identity. |
| Chloride Ion (Cl⁻) | Ion Chromatography (IC) or Potentiometric Titration | Anion separation and quantification (IC) or argentometric titration with AgNO₃ endpoint detection for inorganic chloride impurity. |
| Residual Boc Anhydride | GC-FID or HPLC-UV | Direct quantification of di-tert-butyl dicarbonate residual using GC-FID (volatile) or reversed-phase HPLC-UV (less volatile), based on retention time and calibration. |
| Particle Size Distribution | Laser Diffraction | Measurement of dry or wet dispersed particle size distribution using Mie scattering theory to ensure consistent handling and dissolution behavior. |
| Microbial Contamination | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and absence of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
Technical Specifications of 2-Boc-aminomethylpyrrolidine
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 78-82°C |
| Optical Rotation | -15.0 to -19.0° (c=1, in methanol) |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2-Boc-aminomethylpyrrolidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2-Boc-aminomethylpyrrolidine
Packaging of 2-Boc-aminomethylpyrrolidine
Industrial 2-Boc-aminomethylpyrrolidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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