8-BOC-3,8-DIAZA-BICYCLO[3.2.1]OCTANE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 149771-44-8 |
| Product name | 8-BOC-3,8-DIAZA-BICYCLO[3.2.1]OCTANE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 8-BOC-3,8-DIAZA-BICYCLO[3.2.1]OCTANE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 8-BOC-3,8-DIAZA-BICYCLO[3.2.1]OCTANE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 8-BOC-3,8-DIAZA-BICYCLO[3.2.1]OCTANE
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key pharmaceutical intermediate | Serves as a bicyclic structural unit for synthesizing active pharmaceutical ingredients (APIs) containing diazabicyclic frameworks. |
| Pharmaceutical Chemicals | Synthesis of opioid receptor antagonists | Used to construct azabicyclic scaffolds of morphinan- or benzomorphan-based drugs, participating in nucleophilic substitution or reductive amination reactions. |
| Pharmaceutical Chemicals | Synthesis of respiratory drugs | Applied in synthesizing muscarinic receptor antagonists (e.g., long-acting anticholinergics), introducing basic amine side chains into target molecules. |
| Pharmaceutical Chemicals | Synthesis of central nervous system (CNS) drugs | Employed to build lead compounds containing bicyclic amine structures; its rigid scaffold optimizes pharmacokinetic properties. |
| Research Reagents | Molecular building block | Used in constructing combinatorial chemistry libraries and in structural modification and functionalization studies of drug screening molecules. |
Manufacturing Quality Control of 8-BOC-3,8-DIAZA-BICYCLO[3.2.1]OCTANE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 210-230 nm, calibrated against certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and peak area normalization. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify common organic solvents (e.g., methanol, ethyl acetate, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content by ignition at 700-800 C followed by precise weighing of residual residue. |
| Optical Rotation | Polarimetry | Determination of specific rotation using sodium D-line light source to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement via controlled heating of capillary-packed sample; indicates crystallinity and identity. |
| pH (1% w/v aqueous solution) | pH Meter | Electrochemical measurement of hydrogen ion activity in aqueous suspension to assess protonation state and salt formation. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample using light scattering principles to determine D10, D50, D90 values. |
| Microbial Contamination | Membrane Filtration | Quantitative recovery and cultivation of aerobic microorganisms from filtered sample, followed by colony enumeration per USP <61>. |
Technical Specifications of 8-BOC-3,8-DIAZA-BICYCLO[3.2.1]OCTANE
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 8-BOC-3,8-DIAZA-BICYCLO[3.2.1]OCTANE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 8-BOC-3,8-DIAZA-BICYCLO[3.2.1]OCTANE
Safety Information of 8-BOC-3,8-DIAZA-BICYCLO[3.2.1]OCTANE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 8-BOC-3,8-DIAZA-BICYCLO[3.2.1]OCTANE
Industrial 8-BOC-3,8-DIAZA-BICYCLO[3.2.1]OCTANE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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