China Factory Direct
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| CAS number | 14999-43-0 |
| Product name | Glucosamine sulfate |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Treatment of osteoarthritis; promotion of cartilage repair | Used as the active pharmaceutical ingredient in oral formulations or injectables, participating in the biosynthesis of sulfated glycosaminoglycans |
| Dietary Supplements | Support for joint health; relief of joint discomfort | Formulated into capsules, tablets, or powders, and co-administered with other ingredients (e.g., chondroitin) |
| Food | Functional food additive | Incorporated into health-oriented food products to support bone and joint function |
| Biological Chemical Engineering | Component of cell culture media | Served as a nitrogen source or metabolic precursor in specific microbial or mammalian cell culture systems |
| Test Item | Common Testing Method | Method Overview |
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| Assay (Main Component Analysis) | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol-water or buffer as the mobile phase. D-Glucosamine sulfate is detected by a UV detector at 200–230 nm. The content is calculated using external or internal standard methods. This method is highly specific and sensitive, suitable for quantitative analysis. |
| Purity Test | Gas Chromatography (GC) | After derivatization (e.g., acetylation), GC is used to separate and detect derivatized glucosamine compounds. Coupling with mass spectrometry (GC-MS) enhances identification accuracy, making it suitable for impurity analysis and structural confirmation. |
| Impurity Testing (Related Substances) | High-Performance Liquid Chromatography (HPLC) – Related Substances | Ion-exchange or reversed-phase chromatography is employed to detect potential impurities such as synthesis intermediates, degradation products, and isomers. Impurity levels (total and individual) are evaluated by comparison with reference standards. |
| Heavy Metal Residue Testing | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | After sample digestion, AAS or ICP-MS is used to determine the levels of heavy metals such as lead, cadmium, mercury, and arsenic, ensuring compliance with pharmacopoeial limits (e.g., General Chapter 2341 of the Chinese Pharmacopoeia). |
| Microbial Limit Testing | Total Aerobic Microbial Count, Mold/Yeast Count, Sterility Testing | Performed according to microbial limit test methods in the Chinese Pharmacopoeia to assess compliance with microbial contamination control standards, applicable for oral formulations or active pharmaceutical ingredients. |
| Moisture Content Determination | Karl Fischer Titration | A precise chemical titration method for determining water content in samples. Particularly suitable for hygroscopic substances, this test is critical for controlling product stability and storage conditions. |
| Sulfate Content Determination | Ion Chromatography (IC) or Gravimetric Method | Ion chromatography allows rapid determination of sulfate ion concentration. The gravimetric method (e.g., precipitation as barium sulfate followed by weighing) is accurate but time-consuming, often used for confirmatory testing. |
| Melting Point Determination | Micro Melting Point Apparatus | Determines the melting range by observing the melting behavior of the sample. Used for preliminary identification and purity assessment; a broad melting range may indicate the presence of impurities. |
| Infrared Spectroscopy (IR) Identification | Fourier Transform Infrared Spectroscopy (FTIR) | Compares characteristic absorption peaks (e.g., from functional groups such as -OH, -NH₂, -SO₃⁻) with reference spectra for structural confirmation and consistency evaluation of raw materials. |
| Specific Optical Rotation Determination | Polarimetry | Measures the specific rotation of the sample at a specified wavelength (e.g., sodium D-line), used to confirm optical purity and stereochemical characteristics, an important quality control parameter for chiral compounds. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.2% |
| Optical Rotation | +45° to +55° (c=2, H2O) |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.