Bicine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 150-25-4 |
| Product name | Bicine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Bicine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Bicine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Bicine
| Industry | Application | Process |
|---|---|---|
| Personal Care & Cosmetics | Buffer and pH adjuster | Used as a mild buffering component in shampoos, body washes, and skincare formulations to maintain stable product pH |
| Pharmaceuticals | Cell culture medium component | Employed as a buffering agent in cell culture media to maintain physiological pH conditions |
| Biochemical Research | Protein purification and electrophoresis buffer | Used to prepare buffer systems for isoelectric focusing and electrophoresis applications |
| Water Treatment | Chelating agent assistant | Used in combination with other chelating agents to mitigate interference from metal ions |
| Laboratory Reagents | Reference standard or synthetic intermediate | Applied in laboratories as a biochemical reagent or organic synthesis precursor |
Manufacturing Quality Control of Bicine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | Acid-Base Titration with NaOH | Quantifies free carboxylic acid group via standardized sodium hydroxide titration using phenolphthalein or potentiometric endpoint detection. |
| Water Content | Karl Fischer Titration | Measures trace water by iodine oxidation of sulfur dioxide in methanol, stoichiometrically linked to water content. |
| pH (1% aqueous solution) | pH Potentiometry | Determines hydrogen ion activity in a 10 g/L aqueous solution using calibrated glass electrode and pH meter. |
| Heavy Metals (as Pb) | ICP-OES | Quantifies total heavy metal impurities (e.g., Pb, Cd, Hg, As) after acid digestion via atomic emission spectroscopy at element-specific wavelengths. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic impurities by high-temperature (700–800 °C) incineration followed by weight determination of residual ash. |
| Chloride Impurity | Ion Chromatography (IC) | Separates and quantifies chloride anions using anion-exchange column and suppressed conductivity detection. |
| Related Substances | HPLC with UV Detection | Separates and quantifies structurally related impurities (e.g., diethanolamine, glycine, N-hydroxyethylglycine) using reversed-phase C18 column and UV absorbance at 200–220 nm. |
| Appearance (Solution Clarity) | Visual Inspection against Standard Solutions | Assesses physical clarity and color by visual comparison of a 5% w/v aqueous solution to water and platinum-cobalt standard solutions under controlled lighting. |
| Melting Point | Capillary Melting Point Determination | Determines temperature range of solid-to-liquid transition using calibrated digital melting point apparatus per USP <741>. |
Technical Specifications of Bicine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 168-172°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
| Solubility | Freely soluble in water; slightly soluble in ethanol |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Bicine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Bicine
Packaging of Bicine
Industrial Bicine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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