4-Amino-7H-pyrrolo[2,3-d]pyrimidine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 1500-85-2 |
| Product name | 4-Amino-7H-pyrrolo[2,3-d]pyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 4-Amino-7H-pyrrolo[2,3-d]pyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Amino-7H-pyrrolo[2,3-d]pyrimidine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Amino-7H-pyrrolo[2,3-d]pyrimidine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of kinase inhibitors (e.g., JAK inhibitors) | Used to construct heterocyclic scaffolds and participate in multi-step organic synthesis reactions, such as Suzuki coupling and nucleophilic substitution |
| Pharmaceuticals | Precursor compound for anticancer drug synthesis | Introduces pharmacophoric groups via functional group modification (e.g., alkylation, acylation) to generate candidate drug molecules |
| Pharmaceuticals | Development of anti-inflammatory and immunomodulatory drugs | Serves as a core structural unit for structure–activity relationship (SAR) studies in medicinal chemistry |
| Research | Building block for biologically active molecular probes | Applied in high-throughput screening and target validation assays for small-molecule library synthesis |
Manufacturing Quality Control of 4-Amino-7H-pyrrolo[2,3-d]pyrimidine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by comparison of peak area against a certified reference standard using reversed-phase chromatography and UV detection at 260 nm. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC with UV detection; identification based on retention time matching and relative response factors. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify volatile organic solvents (e.g., methanol, acetone, DMF) based on calibrated external standards. |
| Water Content | Karl Fischer Titration | Volumetric titration using iodine, sulfur dioxide, and base in methanol-based reagent; water reacts stoichiometrically to determine moisture content. |
| Heavy Metals | ICP-OES | Digestion followed by inductively coupled plasma optical emission spectroscopy to simultaneously quantify metals (e.g., Pb, Cd, Ni, Fe) via element-specific emission lines. |
| Chloride Impurity | Ion Chromatography | Separation of chloride anions on an anion-exchange column with suppressed conductivity detection and quantification against chloride standard calibration. |
| Sulfate Impurity | Ion Chromatography | Anion-exchange chromatography with conductivity detection to quantify sulfate ions using external calibration with sodium sulfate standard. |
| Residue on Ignition | Gravimetric Analysis | Ignition of sample at 700-800 C to oxidize organic matter; residue weight measured after cooling in desiccator to determine inorganic ash content. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range over which solid transforms to liquid, indicating purity and identity. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through solution; used to confirm chiral integrity and absence of racemization. |
| Particle Size Distribution | Laser Diffraction | Analysis of scattered laser light intensity pattern from dispersed particles to calculate volume-based size distribution according to Mie theory. |
| Microbial Limits | Membrane Filtration | Filtration of sample solution through sterile membrane, followed by incubation on selective agar media to enumerate aerobic microorganisms and detect specified pathogens. |
Technical Specifications of 4-Amino-7H-pyrrolo[2,3-d]pyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 275-279 °C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 4-Amino-7H-pyrrolo[2,3-d]pyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Amino-7H-pyrrolo[2,3-d]pyrimidine
Safety Information of 4-Amino-7H-pyrrolo[2,3-d]pyrimidine
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 4-Amino-7H-pyrrolo[2,3-d]pyrimidine
Industrial 4-Amino-7H-pyrrolo[2,3-d]pyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply