Z-D-NLE-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 15027-14-2 |
| Product name | Z-D-NLE-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Z-D-NLE-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Z-D-NLE-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Z-D-NLE-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral synthetic intermediates | Used in solid-phase synthesis of peptide-based drugs, serving as protected amino acids in coupling reactions |
| Biochemistry | Peptide chain elongation and protection | Introduces D-configured amino acids in peptide synthesis; amino groups are protected with benzyloxycarbonyl (Z) to control stereoselectivity |
| Organic synthesis | Asymmetric synthesis reagents | Serves as chiral building blocks for constructing complex molecules with defined stereochemical configurations |
Manufacturing Quality Control of Z-D-NLE-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Chiral Purity | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase with UV detection; D-isomer content calculated from enantiomeric peak area ratio. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on the stoichiometric reaction of water with iodine, sulfur dioxide, and base in methanol/pyridine medium. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify common solvents (e.g., methanol, ethyl acetate, toluene) against calibration standards. |
| Heavy Metals | ICP-OES | Multi-element quantification after acid digestion using inductively coupled plasma optical emission spectrometry; total heavy metals reported as Pb equivalent. |
| Residual Chloride | Ion Chromatography | Separation and quantification of chloride anion using suppressed conductivity detection after aqueous extraction. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition observed visually or automatically as the temperature range over which solid-to-liquid phase change occurs. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light at 589 nm (Na D-line) in a solution of known concentration and path length. |
| Appearance | Visual Inspection | Assessment under controlled white light against standard references for color, clarity, and presence of particulates or foreign matter. |
| Loss on Drying | Gravimetric Thermobalance | Mass loss measured after drying at 105 C for 2 hours under vacuum or nitrogen purge. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., deprotected amine, hydrolysis products) using gradient reversed-phase HPLC with UV detection. |
| Residual Palladium | ICP-MS | Ultra-trace quantification of palladium after microwave-assisted acid digestion using inductively coupled plasma mass spectrometry. |
Technical Specifications of Z-D-NLE-OH
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Melting Point | 120-124°C |
| Optical Rotation | +15.0 to +17.0° (c=1, in DMF) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Z-D-NLE-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Z-D-NLE-OH
Packaging of Z-D-NLE-OH
Industrial Z-D-NLE-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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