4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 150728-13-5 |
| Product name | 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine Supplier from China
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Industrial Applications of 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Insecticide intermediate | Prepared via reaction of 4,6-dichloro-5-(2-methoxyphenoxy)pyrimidine with urea derivatives |
| Pharmaceuticals | Pharmaceutical intermediate | Used in the synthesis of biologically active pyrimidine derivatives |
Manufacturing Quality Control of 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
| Detection Item | Common Detection Methods | Method Overview |
|---|---|---|
| Identification (Identity) | HPLC (High-Performance Liquid Chromatography) IR (Infrared Spectroscopy) ¹H NMR (Proton Nuclear Magnetic Resonance) |
Identification by comparing retention times with reference standards under identical chromatographic conditions using HPLC; IR confirms structure through characteristic functional group absorption peaks; ¹H NMR verifies molecular structure by comparing chemical shifts, integral areas, and coupling constants with standard spectra. |
| Content Determination (Assay) | HPLC (High-Performance Liquid Chromatography) | Reverse-phase C18 column is used with mobile phases such as methanol-water or acetonitrile-buffer salt. Detection is performed using a UV detector (typically around 254 nm). The content of the main component is calculated using the external standard method to ensure the purity of the raw material meets specifications (e.g., ≥98.0%). |
| Related Substances | HPLC (High-Performance Liquid Chromatography) | A gradient elution program is used to separate the main peak from potential impurities (such as starting materials, intermediates, by-products, and degradation products). The limits of individual impurities are controlled using area normalization or the main component self-reference method with correction factors (usually ≤0.5% for individual impurities, ≤1.0% for total impurities). |
| Residual Solvents | GC (Gas Chromatography), Headspace Sampling (HS-GC) | According to ICH Q3C guidelines, headspace gas chromatography is used to detect residual organic solvents (such as methanol, dichloromethane, DMF, etc.) from the synthesis process. Quantification is performed using an FID detector, ensuring that the residual levels are below the specified limits. |
| Dry Loss (Loss on Drying) | TGA (Thermogravimetric Analysis) or Atmospheric Constant Temperature Drying | Samples are dried at a specified temperature (e.g., 105°C) until constant weight is achieved. The percentage of mass loss is measured to evaluate water and volatile matter content. Typically, this should be ≤0.5%. |
| Residue on Ignition (Sulphated Ash) | High-Temperature Incineration Method | Samples are treated with sulfuric acid and incinerated at temperatures between 700–800°C until constant weight is achieved. The amount of inorganic impurities is determined, typically requiring ≤0.1%. |
| Heavy Metals | AAS (Atomic Absorption Spectrometry) or ICP-MS (Inductively Coupled Plasma Mass Spectrometry) | According to pharmacopoeia general rules, samples are processed and analyzed using AAS or more sensitive ICP-MS to determine the total content or individual concentrations of elements such as lead, cadmium, mercury, and arsenic, complying with ICH Q3D requirements for elemental impurity control. |
Technical Specifications of 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.3% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
Safety Information of 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
| Pictograms |  |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine
Industrial 4,6-Dichloro-5-(2-methoxyphenoxy)-2,2'-bipyrimidine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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