China Factory Direct
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| CAS number | 150736-71-3 |
| Product name | Carbamic acid, [(1R)-1-(hydroxymethyl)propyl]-, 1,1-dimethylethyl ester (9CI) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key Chiral Intermediate | Used in the synthesis of the anti-HIV drug efavirenz as a starting material or key building block for constructing the chiral structure. |
| Pharmaceutical Chemicals | Chiral Drug Synthesis | Serves as a chiral amino alcohol structural unit for synthesizing other chiral drug molecules containing the (R)-2-amino-1-butanol scaffold. |
| Pharmaceutical Chemicals | Precursor to Asymmetric Synthesis Catalysts/Ligands | Leverages its chiral amino alcohol structure to prepare chiral catalysts or ligands for asymmetric synthesis reactions. |
| Research & Development | Chiral Reference Standard | Used in chiral compound analysis, enantiomeric impurity studies, and as a reference standard in chromatographic analysis. |
| Detection Item | Common Analytical Method | Method Overview |
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| Assay (Purity) | HPLC with UV detection | Quantitative determination using reverse-phase HPLC and UV absorbance at 200-220 nm relative to a certified reference standard. |
| Enantiomeric Purity | Chiral HPLC | Separation of R and S enantiomers on a chiral stationary phase, with UV detection and calculation of enantiomeric excess. |
| Water Content | Karl Fischer titration | Electrochemical titration using iodine generated in situ to quantify water based on stoichiometric reaction with iodine and sulfur dioxide. |
| Residual Solvents | Gas Chromatography (GC) with FID | Separation and quantification of volatile organic solvents (e.g., THF, toluene, ethyl acetate) using capillary GC and flame ionization detection. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion, using inductively coupled plasma mass spectrometry. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using anion-exchange column and suppressed conductivity detection. |
| Residual Palladium | ICP-OES | Quantification of palladium from catalyst residues after microwave-assisted acid digestion, using inductively coupled plasma optical emission spectroscopy. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting conditions. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated digital melting point instrument. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light source to confirm chiral integrity and concentration-corrected enantiomeric identity. |
| pH (1% w/v aqueous solution) | pH Meter | Electrochemical measurement of hydrogen ion activity in a standardized aqueous solution using calibrated pH electrode. |
| Related Substances | HPLC with UV detection | Identification and quantification of structurally related impurities (e.g., deprotected amine, oxidation products) using gradient HPLC and UV detection. |
| Test Item | Specification |
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| Appearance | White to off-white crystalline solid |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 48.0 - 52.0 °C |
| Optical Rotation | +26.0 to +28.0 ° (c=1, in CHCl3) |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.