(S)-2-Methylpyrrolidine-2-carboxylic acid hydrochloride Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1508261-86-6 |
| Product name | (S)-2-Methylpyrrolidine-2-carboxylic acid hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for (S)-2-Methylpyrrolidine-2-carboxylic acid hydrochloride
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk (S)-2-Methylpyrrolidine-2-carboxylic acid hydrochloride Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of (S)-2-Methylpyrrolidine-2-carboxylic acid hydrochloride
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral synthesis intermediate | Used in the synthesis of biologically active drug molecules as a chiral building block for constructing proline-containing structural units |
| Organic synthesis | Substrate for asymmetric catalytic reactions | Participates in multicomponent or cyclization reactions to prepare complex chiral compounds |
| Biochemical research | Synthesis of peptide mimetics | Introduces the (S)-2-methylproline structure to modulate conformational and metabolic stability of peptides |
Manufacturing Quality Control of (S)-2-Methylpyrrolidine-2-carboxylic acid hydrochloride
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and visible impurities under natural light or standard illumination. |
| Melting Point | Capillary Melting Point Determination | Determine the melting temperature range using a melting point apparatus to assess purity and consistency. |
| Specific Rotation | Polarimeter Method | Prepare a solution of known concentration and measure its specific rotation using a polarimeter to verify the optical purity of the (S)-configuration. |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase HPLC (e.g., C18 column) with UV detection (around 210 nm), employing external standard or internal standard method to determine the main component content. |
| Enantiomeric Purity | Chiral High-Performance Liquid Chromatography (Chiral HPLC) | Separate enantiomers using a chiral chromatographic column and determine the ratio of (S)- to (R)-isomers to evaluate optical purity. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Detect potential synthetic intermediates, by-products, or degradation products via gradient or isocratic elution; calculate total impurity levels. |
| Chloride (Cl⁻) | Ion Chromatography or Silver Titration | Ion chromatography precisely measures free chloride ion content; silver titration determines chloride content by titration to confirm the accuracy of the hydrochloride form. |
| Water Content | Karl Fischer Titration | Accurately determine water content using coulometric or volumetric Karl Fischer titration instruments. |
| Loss on Drying | Thermogravimetric Analysis (TGA) or Oven Method | Heat the sample at a specified temperature and measure mass loss to assess volatile components and solvent residues. |
| Residue on Ignition (Sulfated Ash) | Gravimetric Method | After high-temperature ignition, weigh the residual inorganic matter to evaluate inorganic impurity levels. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, determine levels of lead, arsenic, cadmium, mercury, and other heavy metals to ensure compliance with pharmacopoeial limits. |
| Solubility | Solubility Test | Test solubility in water, ethanol, methanol, and other solvents to confirm suitability for intended applications. |
| Structural Confirmation | Nuclear Magnetic Resonance (NMR), Mass Spectrometry (MS) | ¹H NMR, ¹³C NMR, and HRMS are used to confirm molecular structure and consistency with the target compound. |
Technical Specifications of (S)-2-Methylpyrrolidine-2-carboxylic acid hydrochloride
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (HPLC) |
| Optical Rotation | -25.0° to -31.0° (c=1, 1M HCl) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 215°C to 225°C (decomposes) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of (S)-2-Methylpyrrolidine-2-carboxylic acid hydrochloride
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of (S)-2-Methylpyrrolidine-2-carboxylic acid hydrochloride
Safety Information of (S)-2-Methylpyrrolidine-2-carboxylic acid hydrochloride
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of (S)-2-Methylpyrrolidine-2-carboxylic acid hydrochloride
Industrial (S)-2-Methylpyrrolidine-2-carboxylic acid hydrochloride Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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