BOC-ORN(FMOC)-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 150828-96-9 |
| Product name | BOC-ORN(FMOC)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for BOC-ORN(FMOC)-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk BOC-ORN(FMOC)-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of BOC-ORN(FMOC)-OH
| Industry | Application | Process |
|---|---|---|
| Biopharmaceuticals | Dual protecting reagent for ornithine residues in solid-phase peptide synthesis (SPPS), enabling selective removal of either the Fmoc or Boc protecting group | In solid-phase peptide synthesis (SPPS), the Fmoc group is cleaved under mild conditions using a piperidine/DMF solution, while the Boc group remains intact; the Boc group is subsequently removed selectively under acidic conditions (e.g., TFA/DCM), implementing an orthogonal protection strategy |
| Pharmaceutical R&D | Key intermediate for constructing bioactive molecules containing ornithine, including cyclic peptides, antimicrobial peptides, and targeted delivery peptides | As a chiral, dual-protected ornithine derivative, it participates in coupling reactions (e.g., activated by HATU/DIPEA) to incorporate ornithine at specific positions in the peptide chain, preserving stereochemical integrity and enabling subsequent modifications |
Manufacturing Quality Control of BOC-ORN(FMOC)-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification by peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 254 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities using gradient reversed-phase HPLC with UV detection. |
| Residual Solvents | GC-FID | Identification and quantification of volatile organic solvents based on retention time and peak area relative to internal standard calibration. |
| Water Content | Karl Fischer Titration | Electrochemical titration using iodine generated in situ to react stoichiometrically with water in the sample. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific rotation using a polarimeter to confirm chiral integrity and enantiomeric purity. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (e.g., Pb, Cd, Hg, As) after acid digestion and plasma ionization. |
| Residual Chloride | Ion Chromatography | Separation and quantification of chloride ions using anion-exchange column and conductivity detection. |
| Residual Fmoc Group | HPLC-UV | Specific assay for unreacted or cleaved Fmoc moiety via UV absorbance at 301 nm under optimized chromatographic conditions. |
| Residual Boc Group | HPLC-UV | Quantification of residual Boc protecting group by UV detection following acidic hydrolysis and derivatization if needed. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution based on light scattering patterns from dispersed particles. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after controlled heating under specified temperature and vacuum conditions. |
| Microbial Contamination | Membrane Filtration | Enumeration of aerobic microorganisms by filtration, membrane transfer to culture media, and colony counting after incubation. |
Technical Specifications of BOC-ORN(FMOC)-OH
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 178–182°C |
| Optical Rotation | -7.0 to -4.0° (c=1, DMF) |
| Identification (NMR) | Conforms to reference spectrum |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of BOC-ORN(FMOC)-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of BOC-ORN(FMOC)-OH
Packaging of BOC-ORN(FMOC)-OH
Industrial BOC-ORN(FMOC)-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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