China Factory Direct
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| CAS number | 1509-92-8 |
| Product name | N-Acetyl-D-methionine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Chiral synthetic intermediates | Used to prepare drug molecules with defined stereochemistry; employed in asymmetric synthesis reactions |
| Biochemical research | Amino acid derivative probes | Applied as labels or tracers in studies of protein synthesis and metabolic pathways |
| Pharmaceutical manufacturing | Antitumor drug precursors | Serve as building blocks in multistep syntheses for developing novel anticancer compounds |
| Organic synthesis | Supporting reagents | Protect the thiol group of methionine side chains to enable selective reactions in complex molecule synthesis |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 205 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separation of D- and L-enantiomers on a chiral stationary phase, with UV detection to determine enantiomeric excess. |
| Loss on Drying | Gravimetric (105 C oven drying) | Mass loss measured after drying sample at 105 C until constant weight, indicating volatile content including water and solvents. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration with iodine-based reagent; water reacts stoichiometrically to determine trace moisture. |
| Residue on Ignition | Gravimetric (500-600 C ashing) | Mass of inorganic residue remaining after high-temperature incineration, indicating inorganic impurities. |
| Heavy Metals | ICP-OES | Multi-element quantification of Pb, Cd, Hg, As, and other heavy metals after acid digestion and plasma emission spectroscopy. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride anions using suppressed conductivity detection after aqueous extraction. |
| Sulfate Impurity | Ion Chromatography | Separation and quantification of sulfate anions using suppressed conductivity detection after aqueous extraction. |
| Related Substances | HPLC-UV | Detection and quantification of structurally related impurities (e.g., D-methionine, N-acetyl-L-methionine, acetic anhydride residues) by gradient HPLC. |
| pH (1% aqueous solution) | Potentiometric pH measurement | Determination of hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution, used to confirm identity and enantiomeric integrity. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic mesophilic bacteria and absence of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial guidelines. |
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 168–172°C |
| Optical Rotation | +18° to +22° (c=1, in 1M HCl) |
| Total Impurities | <=1.5% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.