4-Difluoromethoxy-3-hydroxybenzaldehyde Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 151103-08-1 |
| Product name | 4-Difluoromethoxy-3-hydroxybenzaldehyde |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeElectronic Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Difluoromethoxy-3-hydroxybenzaldehyde
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Difluoromethoxy-3-hydroxybenzaldehyde Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Difluoromethoxy-3-hydroxybenzaldehyde
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Used as a pharmaceutical intermediate in the synthesis of bioactive molecules, including anti-inflammatory and antitumor agents | Organic synthesis, catalytic reactions |
| Agrochemicals | Used as an intermediate in the preparation of high-efficacy, low-toxicity pesticides | Condensation reactions, fluorination reactions |
| Materials Science | Used as a monomer or modifier for synthesizing fluorinated polymeric materials | Polymerization reactions, functionalization modifications |
| Electronic Chemicals | Used as a fluorinated intermediate in liquid crystal materials or electronic devices | Fine chemical synthesis, purification processes |
Manufacturing Quality Control of 4-Difluoromethoxy-3-hydroxybenzaldehyde
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the color and condition of the sample (e.g., white to light yellow crystalline powder), and check for foreign matter or clumping due to moisture absorption. |
| Purity (Content) | High-Performance Liquid Chromatography (HPLC) | Use a C18 reverse-phase chromatographic column with a UV detector (e.g., 254 nm or 280 nm), and quantify the main component using external standard or area normalization methods. |
| Related Substances (Impurities) | HPLC (Gradient Elution) | Separate the main peak from potential impurity peaks using a gradient elution program, and assess impurity limits by relative retention time and peak area. |
| Moisture | Karl Fischer Titration | Determine moisture content using coulometric or volumetric methods, ensuring compliance with drying loss or moisture limit requirements. |
| Residual Solvents | Gas Chromatography (GC-FID/HS-GC) | Analyze by headspace sampling or direct injection using capillary columns and FID detector to quantify residual organic solvents (e.g., methanol, ethyl acetate, etc.). |
| Melting Point | Capillary Melting Point Apparatus | Determine the melting temperature range of the sample as a physical constant for identification and preliminary purity assessment. |
| Structural Confirmation | Nuclear Magnetic Resonance (NMR), Infrared Spectroscopy (IR), Mass Spectrometry (MS) | Confirm the hydrogen and carbon skeleton using ¹H-NMR and ¹³C-NMR; confirm functional groups (aldehyde, phenolic hydroxyl, ether) using IR; confirm molecular weight and fragment characteristics using MS. |
| Heavy Metals | ICP-MS or Atomic Absorption Spectrometry (AAS) | Determine residual levels of lead, cadmium, arsenic, mercury, etc., after digestion according to pharmacopoeia methods, ensuring compliance with ICH Q3D limits. |
| Drying Loss | Oven Drying Method | Dry at a specified temperature (e.g., 105°C) until constant weight, calculate the percentage of mass loss to evaluate the content of volatile substances. |
| pH Value (if dissolved in solution) | pH Meter Measurement | Dissolve the sample in a specified solvent (e.g., water or ethanol-water solution), and measure the pH to assess acidity, alkalinity, stability, or corrosiveness. |
Technical Specifications of 4-Difluoromethoxy-3-hydroxybenzaldehyde
| Test Item | Specification |
|---|---|
| Appearance | White to Off- white powder |
| Melting point | 87-91℃ |
| Water content | ≤0.5% |
| Impurity1 | ≤0.1% |
| Impurity2 | ≤0.1% |
| Single unknown impurity | ≤0.2% |
| Total impurity | ≤0.5% |
| Residual solvents（N,N-dimethylformamide） | ≤0.088% |
| Residual solvents（Ethyl acetate） | ≤0.5% |
| Residual solvents（Normal heptane） | ≤0.5% |
| Purity(HPLC) | ≥99.0% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Difluoromethoxy-3-hydroxybenzaldehyde
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Difluoromethoxy-3-hydroxybenzaldehyde
Safety Information of 4-Difluoromethoxy-3-hydroxybenzaldehyde
| Pictograms |   |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Difluoromethoxy-3-hydroxybenzaldehyde
Industrial 4-Difluoromethoxy-3-hydroxybenzaldehyde Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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