3-Hydroxy-2-nitropyridine Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 15128-82-2 |
| Product name | 3-Hydroxy-2-nitropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 3-Hydroxy-2-nitropyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3-Hydroxy-2-nitropyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3-Hydroxy-2-nitropyridine
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Synthesis of anti-tuberculosis drug intermediates | Used as a key intermediate in constructing nitrogen-containing heterocyclic drugs, enabling preparation of biologically active pyridine derivatives |
| Agrochemicals | Intermediate for insecticide and fungicide synthesis | Applied in synthesizing novel nitro-pyridine-based agrochemicals, with functional groups introduced via substitution or cyclization reactions |
| Organic Synthesis | Raw material for specialty chemical synthesis | Employed as a multifunctional compound (bearing hydroxyl and nitro groups) in coupling, reduction, and condensation reactions to prepare complex organic molecules |
Manufacturing Quality Control of 3-Hydroxy-2-nitropyridine
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Utilizes a C18 reversed-phase column with a mobile phase of methanol-water or acetonitrile-water (containing a small amount of acid such as phosphoric or formic acid). Detection is performed using a UV detector at wavelengths between 250–280 nm. Quantification is achieved via external standard or internal standard method to determine the main component content. |
| Purity Analysis | HPLC-UV / HPLC-DAD | Assesses total impurities using area normalization or percentage peak area methods. DAD provides spectral confirmation, ensuring no co-elution interference from target compounds. |
| Impurity Testing (Organic Impurities) | HPLC-MS / UPLC-MS | Uses ultra-performance liquid chromatography coupled with mass spectrometry to identify and quantify process-related impurities (e.g., unreacted raw materials, by-products, degradation products), with sensitivity reaching ppm levels. |
| Moisture Content Determination | Karl Fischer Titration | Measures trace moisture using either volumetric or coulometric methods, suitable for samples dissolved in organic solvents. Complies with pharmacopeial standards (e.g., USP/EP), ensuring moisture content remains below specified limits (e.g., ≤0.5%). |
| Melting Point Determination | Capillary Melting Point Apparatus | Determined according to pharmacopeial methods, with a melting range typically around 120–125°C. Used for preliminary identification and purity assessment; a narrow melting range indicates high purity. |
| UV Absorption Characteristics | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Sample solution prepared in ethanol or methanol, scanned across 200–400 nm. Characteristic absorption peaks (e.g., ~260 nm, ~310 nm) are used for qualitative confirmation and concentration estimation. |
| Inorganic Impurities (e.g., Chloride, Sulfate) | Sulfate/Chloride Limit Test | Conducted per general methods in the Chinese Pharmacopoeia. Results compared visually via turbidity or colorimetry to control inorganic impurities within specified limits (e.g., chloride ≤0.01%). |
| Residual Solvents | Gas Chromatography (GC-FID / GC-MS) | Employs headspace or direct injection to detect residual organic solvents (e.g., ethanol, acetone, dichloromethane) from manufacturing processes. Complies with ICH Q3C guidelines. |
| Polymorphic Analysis (if applicable) | X-Ray Powder Diffraction (XRPD) | Used to confirm the presence or absence of polymorphism, ensuring consistent physical properties across batches—particularly critical for solid dosage form raw materials. |
| pH Value (Aqueous Solution) | Precise pH Meter | Sample dissolved in purified water; pH measured (typically slightly acidic due to phenolic hydroxyl and nitro groups). Used for process monitoring and stability evaluation. |
Technical Specifications of 3-Hydroxy-2-nitropyridine
| Test Item | Specification |
|---|---|
| Appearance | Purple to yellow powder |
| Purity | ≥98.0% |
| Water | ≤0.5% |
| Melting point | 69~71°C |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 3-Hydroxy-2-nitropyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3-Hydroxy-2-nitropyridine
Packaging of 3-Hydroxy-2-nitropyridine
Industrial 3-Hydroxy-2-nitropyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply