2,6-Difluoropyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1513-65-1 |
| Product name | 2,6-Difluoropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 2,6-Difluoropyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 2,6-Difluoropyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 2,6-Difluoropyridine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Serves as a key intermediate in the synthesis of novel pesticides | Condenses with specific amine compounds to generate biologically active pesticide molecules |
| Pharmaceuticals | Acts as an important precursor in the synthesis of certain drugs | Undergoes a series of chemical modifications—including substitution and cyclization—to produce the target drug molecule |
| Materials Science | Used to prepare functional polymeric materials or specialty coatings | Introduces the 2,6-difluoropyridine moiety into material structures via polymerization or other crosslinking techniques |
| Fine Chemicals | Serves as an important reagent in organic synthesis | Participates in various organic transformations, including nucleophilic substitution and coupling reactions |
Manufacturing Quality Control of 2,6-Difluoropyridine
| Detection Item | Common Detection Method | Method Overview |
|---|---|---|
| Purity (Main Component Content) | High-Performance Liquid Chromatography (HPLC) | Uses a C18 reverse-phase chromatographic column, with methanol-water or acetonitrile-water as the mobile phase, and a UV detector (220–254 nm) to measure the main peak area. The content is calculated using external standard or internal standard methods, suitable for high-precision quantitative analysis. |
| Purity (Main Component Content) | Gas Chromatography (GC) | Applicable for volatile 2,6-difluoropyridine. Uses capillary columns (e.g., DB-5 or HP-5), FID detector, and quantifies by comparing retention time with a reference standard, using area normalization or external standard method. |
| Impurity Analysis (Organic Impurities) | HPLC-UV / HPLC-MS | HPLC separation combined with UV or mass spectrometry detection identifies and quantifies potential unreacted raw materials (e.g., 2,6-dichloropyridine), fluorinated by-products, degradation products, etc. MS provides structural confirmation. |
| Water Content | Karl Fischer Titration | Utilizes an iodine-sulfur dioxide-pyridine-methanol system that reacts quantitatively with water. Water content is determined by electrochemical or endpoint methods, suitable for controlling ≤0.1% moisture content, meeting pharmacopoeia requirements. |
| Fluorine Content | Ion-Selective Electrode (ISE) or Ion Chromatography | Samples are converted into fluoride ions via alkaline fusion or bomb combustion. Fluoride ion content is measured using a fluoride ion-selective electrode or ion chromatography (anion exchange column, eluent: NaHCO₃/Na₂CO₃), verifying the completeness of fluorine substitution. |
| Melting Point | Melting Point Apparatus | Determines the melting point range using capillary method or automatic melting point apparatus (literature value ≈ -10°C to -8°C, liquid, commonly measures freezing point). Used for preliminary identification and purity assessment (impurities lower the melting range). |
| Appearance and Color | Visual Inspection + Spectrophotometry | Observes the sample as a colorless to slightly yellow transparent liquid. If necessary, uses a UV-Vis spectrophotometer in the 200–400 nm range to detect any abnormal absorption peaks, assessing colored impurities. |
| Residual Solvents | GC-MS / HS-GC (Headspace Gas Chromatography) | Uses headspace sampling technique to detect residual organic solvents such as acetone, ethanol, acetonitrile, and DMF from the production process. Quantification follows ICH Q3C standards to ensure compliance with residual limits. |
| pH Value (Aqueous Solution) | Glass Electrode pH Meter | Dissolves a small amount of the sample in water (note its weak basicity), and measures the pH of the aqueous solution using a calibrated pH meter (theoretical pH ≈ 6–7), used to assess contamination from acidic or basic impurities. |
| Heavy Metal Residue | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Afters wet digestion of the sample, AAS or ICP-MS is used to determine the content of heavy metals such as lead, cadmium, mercury, and arsenic, ensuring compliance with pharmaceutical or electronic-grade raw material standards (e.g., ≤10 ppm). |
Technical Specifications of 2,6-Difluoropyridine
| Test Item | Specification |
|---|---|
| Appearance | Colorless to almost colorless clear liquid |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.445–1.455 |
| Relative Density (20°C/25°C) | 1.21–1.23 g/cm³ |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 2,6-Difluoropyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 2,6-Difluoropyridine
Packaging of 2,6-Difluoropyridine
Industrial 2,6-Difluoropyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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