China Factory Direct
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| CAS number | 15159-40-7 |
| Product name | 4-Morpholinecarbonyl chloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Pharmaceutical Intermediates | Used as an amino protecting agent or acylating reagent in the synthesis of antibiotic and antitumor drug molecules. |
| Agrochemicals | Agrochemical Intermediates | Applied in the synthesis of morpholine-containing fungicides or insecticides, facilitating construction of key functional groups. |
| Organic Synthesis | Raw Material for Active Ester Synthesis | Reacted with alcohols or phenols to prepare corresponding carbonate derivatives. |
| Polymer Materials | Monomer for Polymer Modification | Participates in polymerization reactions or serves as a capping agent to introduce morpholino groups, thereby enhancing polymer solubility or stability. |
| Test Item | Common Test Methods | Method Overview |
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| Appearance | Visual Inspection | Observe the color, physical state, and clarity of the sample. It should normally be a clear, colorless to light yellow liquid, without suspension. |
| Content (Purity) | Gas Chromatography (GC) or High-Performance Liquid Chromatography (HPLC) | Using an appropriate chromatographic column and detector (e.g., FID or UV), quantify the main component by comparing retention time and peak area with reference standards. |
| Structure Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Confirm the compound structure using ¹H-NMR and ¹³C-NMR, verifying characteristic peaks of the morpholine ring and carbonyl chloride group. |
| Water Content | Karl Fischer Titration | Determine trace moisture in the sample, which is critical as 4-morpholinecarbonyl chloride is prone to hydrolysis. |
| Chlorine Content (Active Chlorine) | Volumetric Analysis with Silver Nitrate (or Ion Chromatography) | Determine the organic chlorine content via titration or instrumental analysis to evaluate the reactivity of the acyl chloride group. |
| Residual Solvents | Gas Chromatography (GC) | Detect possible residual organic solvents (e.g., methylene chloride, ethyl acetate) from the manufacturing process, in compliance with ICH limits. |
| Acid Value/Free Acid | Acid-Base Titration | Titrate free acid (e.g., HCl) in the sample using a standard base solution to indicate the degree of acyl chloride hydrolysis. |
| Melting Point/Boiling Point | Melting Point Apparatus or Boiling Point Determination | Although a liquid, boiling point or refractive index may be measured for identification; thermal behavior can also be analyzed using Differential Scanning Calorimetry (DSC). |
| Impurity Analysis | HPLC or GC-MS | Separate and identify possible synthetic by-products or degradation impurities, such as morpholine dimers or hydrolyzed amide products. |
| Density/Refractive Index | Densitometer or Refractometer | Physical constant testing, used for rapid identification and batch consistency verification. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless to light yellow clear liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Refractive Index (n20/D) | 1.495–1.505 |
| Odor | Characteristic pungent odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.