China Factory Direct
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| CAS number | 15250-46-1 |
| Product name | 4-IODOPHENYLACETIC ACID ETHYL ESTER |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Material GradeSpecialty GradeIndustrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Intermediates | Key intermediate for synthesizing anticancer drugs (e.g., tyrosine kinase inhibitors) | Introduces iodinated aryl structures via palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) |
| Organic Synthesis | Preparation of 4-iodophenylacetic acid and derivatives for constructing complex molecules containing iodinated aryl rings | Acidification following alkaline hydrolysis (NaOH/MeOH–H₂O) to yield 4-iodophenylacetic acid; or direct participation in metallation/halogen exchange reactions |
| Materials Science | Structural building block for liquid crystal monomers or organic optoelectronic materials (e.g., OLED hole-transport layers) | Functional side chains introduced via ester group transformation (e.g., aminolysis, reduction) or further functionalization of the iodine atom (e.g., borylation, cyanation) |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | GC-FID or HPLC-UV | Quantitative determination using calibrated chromatographic separation and detector response against reference standard. |
| Related Substances | HPLC-UV with gradient elution | Separation and detection of structurally similar impurities using reversed-phase HPLC and UV absorbance. |
| Residual Solvents | GC-FID with headspace sampling | Identification and quantification of volatile organic solvents based on retention time and peak area relative to standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration measuring water via iodine-sulfur dioxide reaction in anhydrous methanol-based medium. |
| Acid Value | Acid-Base Titration with NaOH | Neutralization of free carboxylic acid groups using standardized sodium hydroxide solution and potentiometric endpoint detection. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element detection of trace metal contaminants after acid digestion, based on element-specific atomic emission intensities. |
| Chloride Impurity | Ion Chromatography (IC) | Separation and quantification of chloride ions using ion-exchange column and suppressed conductivity detection. |
| Iodine Content | Oxidimetric Titration (with Na2S2O3) | Oxidation of iodide to iodine followed by back-titration of liberated iodine with standardized sodium thiosulfate. |
| Appearance | Visual Inspection | Assessment of physical state, color, and clarity against established reference standards under controlled lighting. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid phase transition temperature range using calibrated capillary tube method. |
| Residue on Ignition | Gravimetric Analysis | Measurement of non-volatile inorganic residue after high-temperature ashing and weighing. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation of plane-polarized light induced by chiral centers in solution at specified wavelength and temperature. |
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 65-69°C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.