4-IODO-2-FLUORO-3-FORMYLPYRIDINE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 153034-82-3 |
| Product name | 4-IODO-2-FLUORO-3-FORMYLPYRIDINE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-IODO-2-FLUORO-3-FORMYLPYRIDINE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-IODO-2-FLUORO-3-FORMYLPYRIDINE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-IODO-2-FLUORO-3-FORMYLPYRIDINE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of kinase inhibitor drugs | Coupling reactions, nucleophilic substitution reactions |
| Pharmaceuticals | R&D of anticancer and antitumor agents | Functional group transformations, condensation reactions |
| Chemicals | Synthesis of complex heterocyclic compounds | Cross-coupling reactions (e.g., Suzuki coupling) |
Manufacturing Quality Control of 4-IODO-2-FLUORO-3-FORMYLPYRIDINE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV or UPLC-MS | Separation and quantification of structurally related impurities (e.g., dehalogenated, oxidized, or hydrolyzed by-products) using gradient elution and UV or mass-selective detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents (e.g., DMF, THF, ethyl acetate) based on calibrated external standards. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pd, Ni, Fe, Pb) after microwave-assisted acid digestion, leveraging high sensitivity and isotopic resolution. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with pyridine–SO₂–methanol reagent. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by ignition at 700–800 °C followed by precise weighing of residual non-volatile matter. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition measurement using controlled heating rate; sharp melting range indicates crystalline purity and absence of eutectic impurities. |
| Optical Rotation | Polarimetry | Measurement of specific rotation at sodium D-line (589 nm) to assess chiral integrity (if applicable) and detect racemization or asymmetric degradation. |
| Iodine Content | ICP-OES | Quantitative determination of total iodine after alkaline fusion or microwave digestion, using characteristic atomic emission lines (e.g., 178.276 nm). |
| Aldehyde Content | Potentiometric Titration with Hydroxylamine Hydrochloride | Derivatization of aldehyde group to oxime with excess hydroxylamine, followed by back-titration of unreacted acid to determine aldehyde equivalents. |
| pH of Aqueous Suspension | pH Meter (10% w/v suspension in water) | Direct potentiometric measurement reflecting acidic/basic impurities or hydrolytic degradation products affecting proton exchange. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder dispersion using Mie scattering theory to determine D10, D50, D90 values relevant to handling and formulation consistency. |
| Microbial Contamination | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per pharmacopeial guidelines (USP <61>/<62>). |
Technical Specifications of 4-IODO-2-FLUORO-3-FORMYLPYRIDINE
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 112–116°C |
| Identification (NMR) | Consistent with structure |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-IODO-2-FLUORO-3-FORMYLPYRIDINE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-IODO-2-FLUORO-3-FORMYLPYRIDINE
Safety Information of 4-IODO-2-FLUORO-3-FORMYLPYRIDINE
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-IODO-2-FLUORO-3-FORMYLPYRIDINE
Industrial 4-IODO-2-FLUORO-3-FORMYLPYRIDINE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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