2-Chloromethyl-3-methyl-4-(3-methoxypropoxy)pyridine hydrochloride Bulk Supply for Industrial Use
China Factory Direct
 |
|
| CAS number | 153259-31-5 |
| Product name | 2-Chloromethyl-3-methyl-4-(3-methoxypropoxy)pyridine hydrochloride |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
QUOTE TYPE
PACKAGING TYPE
TOTAL QUANTITY(KG)
PREFERRED SHIPPING METHOD
YOUR COMPANY
YOUR E-MAIL
Calculate Summary
Based on current marketvolatility and material availability.
Documents We Provide for 153259-31-5
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 153259-31-5 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 153259-31-5
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for synthesizing gastric acid secretion inhibitors (e.g., proton pump inhibitors such as rabeprazole and ilaprazole) | Used to construct the pyridine ring side chain structure |
Manufacturing Quality Control of 153259-31-5
| Detection Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state, and presence of visible foreign particles under natural light or standard illumination. |
| Identification | Infrared Spectroscopy (IR) | Compare the sample’s spectrum with reference standards to confirm consistency in functional groups and molecular structural characteristic peaks. |
| Nuclear Magnetic Resonance Spectroscopy (¹H-NMR, ¹³C-NMR) | Assess chemical shifts and coupling constants in hydrogen and carbon spectra to verify the authenticity of the compound’s structure. | |
| Mass Spectrometry (MS) | Determine molecular ion peaks (e.g., ESI-MS or EI-MS) and fragment ions to confirm molecular weight and assist in structural elucidation. | |
| Content Determination | High-Performance Liquid Chromatography (HPLC) | Use reversed-phase columns (e.g., C18) with UV detection; quantify main component content via external standard or internal standard method to assess purity. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Employ gradient or isocratic elution to detect process impurities and degradation products; calculate individual impurity peak areas and report maximum single impurity and total impurities. |
| Water Content | Karl Fischer Titration | Accurately determine moisture content using titration; suitable for hygroscopic salts such as hydrochlorides. |
| Drying Loss | Thermogravimetric Analysis (TGA) or Oven Method | Dry the sample at a specified temperature for a set time, then measure the percentage of mass loss to assess volatile components or solvent residues. |
| Residue on Ignition | Sulfated Ash Method | After high-temperature incineration, treat the residue with sulfuric acid and weigh the remaining ash to evaluate inorganic impurity levels. |
| Chloride (Chloride Ion) | Ion Chromatography (IC) or Silver Titration | Detect free chloride ions or inorganic chloride impurities in hydrochloride salts to ensure compliance with pharmacopeial limits. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Determine residual levels of toxic elements such as lead, cadmium, mercury, and arsenic to meet ICH Q3D elemental impurity limits. |
| Residual Solvents | Gas Chromatography (GC) | Test for organic solvents (e.g., methanol, ethanol, acetone, dichloromethane) used during manufacturing according to ICH Q3 guidelines. |
| Melting Point | Capillary Melting Point Method | Determine the temperature range at which the solid transitions into liquid, serving as a preliminary indicator of purity and material characteristics. |
| pH (Solution) | pH Meter Measurement | Prepare a solution of known concentration and measure its acidity/alkalinity using a calibrated pH meter. |
| Polymorph Analysis | X-Ray Powder Diffraction (XRPD) | Analyze the crystalline structure of solid samples to confirm the absence or presence of polymorphic forms, ensuring batch-to-batch consistency (where applicable). |
| Particle Size Distribution | Laser Diffraction (LD) | For active pharmaceutical ingredients, determine particle size distribution, which affects dissolution rate and formulation performance. |
Technical Specifications of 153259-31-5
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142°C - 146°C |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
|
|
Download COA of 153259-31-5
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 153259-31-5
Packaging of 153259-31-5
Industrial 153259-31-5 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
Use Bulk
Supply Factory
Direct ISO 9001
Certified Samples
Available Stable
Supply