China Factory Direct
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| CAS number | 154057-56-4 |
| Product name | 3-(Bromomethyl)-2-cyclopropyl-4-(4'-fluorophenyl)quinoline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate | Used in the synthesis of specific pharmaceuticals, including anticancer agents |
| Medical Research | Biological Activity Studies | Applied to investigate biological activity and mechanisms of action at the cellular level |
| Materials Science | Novel Material Synthesis | Employed as a building block in organic synthesis for designing and synthesizing new functional materials |
| Test Item | Commonly Used Testing Method | Method Overview |
|---|---|---|
| Structural Confirmation | Nuclear Magnetic Resonance (NMR) | Analyzes chemical shifts and couplings of hydrogen, carbon, and fluorine atoms via ¹H NMR, ¹³C NMR, 19F NMR, etc., to confirm molecular structure. |
| Purity Determination | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column and UV detector (e.g., 254 nm), with external standard or area normalization method for quantifying the purity of the main component. |
| Impurity Analysis | HPLC-UV / HPLC-MS | After HPLC separation, impurities are identified and quantified using UV or mass spectrometry detection, including organic impurities such as starting materials, by-products, and degradation products. |
| Residual Solvents | Gas Chromatography (GC) | Headspace or direct injection with FID detector, quantifies residual solvents (e.g., dichloromethane, ethanol) according to ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration | Determines water content in the sample using volumetric or coulometric methods, ensuring compliance with limits for loss on drying or moisture content. |
| Melting Point | Capillary Melting Point Apparatus | Measures the melting temperature range of the compound, serving as a physical constant to assist in assessing purity and crystal form consistency. |
| Heavy Metal Residues | ICP-MS or Atomic Absorption Spectroscopy (AAS) | After sample digestion, determines residues of elements such as lead, cadmium, mercury, and arsenic, in compliance with ICH Q3D elemental impurity limits. |
| Chiral Purity (if applicable) | Chiral HPLC | If the molecule contains a chiral center (e.g., introduced by cyclopropyl substitution), chiral columns are used to separate enantiomers and assess optical purity. |
| Loss on Drying | Oven Drying Method | Determines mass loss after drying at a specified temperature (e.g., 105°C) to assess content of volatile substances or adsorbed water. |
| Residue on Ignition | Muffle Furnace Ashing Method | Weighs inorganic residue after high-temperature ignition to control levels of inorganic salts or metal catalyst residues. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline solid |
| Purity | >=98.5% (HPLC) |
| Total Impurities | <=1.5% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Melting Point | 142–146°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.