(S)-2-(3-((2-Isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 154212-61-0 |
| Product name | (S)-2-(3-((2-Isopropylthiazol-4-yl)methyl)-3-methylureido)-3-methylbutanoic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 154212-61-0
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 154212-61-0 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 154212-61-0
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for novel insecticides, used in synthesizing high-efficacy, low-toxicity organophosphorus or thiazole-based insecticides | Multi-step organic synthesis involving key reactions including acylation, alkylation, and cyclization to construct the target molecular structure |
| Pharmaceuticals | Used to synthesize bioactive peptides or drug precursors, potentially supporting antitumor or antimicrobial drug development | Acts as an amino acid derivative in solid-phase or solution-phase peptide synthesis for peptide chain assembly |
| Chemical Intermediates | Key intermediate in fine chemical synthesis, employed to construct complex molecular architectures containing a thiazole ring | Structural modification via selective functional group transformations, such as nucleophilic substitution and coupling reactions |
Manufacturing Quality Control of 154212-61-0
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reversed-phase HPLC with UV detection at 210-230 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of structurally related impurities using gradient HPLC-UV, with identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace gas chromatography with flame ionization detection to quantify residual solvents (e.g., methanol, acetone, ethyl acetate) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content based on stoichiometric reaction with water. |
| Heavy Metals | ICP-MS | Multi-element quantification of toxic metals (Pb, Cd, As, Hg, Ni) after acid digestion, using inductively coupled plasma mass spectrometry for sub-ppb sensitivity. |
| Chloride Impurity | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction and filtration. |
| Residue on Ignition | Gravimetric Analysis | Determination of inorganic ash content by high-temperature incineration followed by precise weighing of the residue. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity of the L-valine moiety. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine D10, D50, D90 values based on light scattering intensity vs. angle. |
| pH of Aqueous Suspension | Potentiometric pH Measurement | Determination of pH in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode and pH meter. |
| Microbial Limits | Membrane Filtration | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) per USP <61> and <62>. |
| Crystal Form | X-Ray Powder Diffraction | Identification and verification of crystalline polymorph by comparing diffraction pattern (2-theta angles and intensities) with reference standard. |
Technical Specifications of 154212-61-0
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (by LC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 148–152°C |
| Optical Rotation | -114° to -110° (c=1, in DMF) |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 154212-61-0
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 154212-61-0
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Industrial 154212-61-0 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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