China Factory Direct
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| CAS number | 1544-68-9 |
| Product name | 4-FLUOROPHENYL ISOTHIOCYANATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Used in the synthesis of fluorinated aromatic amine intermediates, such as antidepressants and antipsychotics | Acts as an isothiocyanate reagent in nucleophilic substitution or cyclization reactions to construct fluorinated heterocyclic structures |
| Agricultural Chemicals | Used as a pesticide intermediate for synthesizing biologically active fluorinated arylthiourea compounds | Condenses with amines to generate thiourea derivatives for developing novel herbicides or insecticides |
| Analytical Chemistry | Used as a derivatization reagent to introduce fluorescent or UV-absorbing tags onto amino acids and amines, enhancing detection sensitivity | Reacts with primary or secondary amines under mild conditions to form stable thiourea derivatives suitable for HPLC or LC-MS analysis |
| Materials Science | Used as a precursor for fluorinated functional materials, such as liquid crystal molecules or polymer monomers | Participates in click chemistry or step-growth polymerization to incorporate fluorophenyl isothiourea structural units for tuning material properties |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at ~254 nm, comparing peak area against a certified reference standard. |
| Residual Solvents (e.g., acetone, toluene) | GC-FID | Separation and quantification of volatile organic solvents by gas chromatography with flame ionization detection using internal/external standards. |
| Water Content | Karl Fischer Titration | Electrochemical titration based on the reaction of iodine with water in a methanol-based reagent, measuring endpoint coulometrically or volumetrically. |
| Heavy Metals (Pb, Cd, Hg, As) | ICP-MS | Multi-element quantification via inductively coupled plasma mass spectrometry after acid digestion and matrix-matched calibration. |
| Chloride Impurity | Ion Chromatography (IC) | Separation of chloride anions on an anion-exchange column with suppressed conductivity detection, calibrated against NaCl standards. |
| Related Substances (e.g., 4-fluoroaniline, thiourea derivatives) | HPLC-UV/DAD | Identification and quantification of structurally related impurities using gradient HPLC with diode-array detection and spectral library matching. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate per USP <741>. |
| Appearance (Color & Clarity) | Visual Inspection (against APHA/Hazen scale) | Comparison of solution color and clarity in specified solvent (e.g., ethanol) to standardized platinum-cobalt color scales. |
| Residue on Ignition | Gravimetric Analysis | Weighing of non-volatile residue remaining after high-temperature ashing (700–800 °C) of a weighed sample. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light passing through a solution, corrected for concentration and path length per Ph. Eur. 2.2.7. |
| Test Item | Specification |
|---|---|
| Appearance | White to pale yellow crystalline powder |
| Purity | >=98.0% (GC) |
| Water Content (KF) | <=0.5% |
| Melting Point | 42–46°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Odor | Characteristic pungent odor |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.