4-(Difluoromethoxy)nitrobenzene Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 1544-86-1 |
| Product name | 4-(Difluoromethoxy)nitrobenzene |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-(Difluoromethoxy)nitrobenzene
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-(Difluoromethoxy)nitrobenzene Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-(Difluoromethoxy)nitrobenzene
| Industry | Application | Process |
|---|---|---|
| Pesticides | Key intermediate in the synthesis of sulfluramid | Sulfluramid is produced via multi-step reactions including introduction of a difluromethoxy group onto the nitrobenzene ring, followed by reduction, diazotization, and sulfonation |
| Pharmaceuticals | Potential fluorinated structural motif for constructing metabolically stable aryloxy fragments in drug molecules | Serves as a modification site on aryl fluoroether lead compounds and participates in coupling reactions (e.g., Suzuki, Ullmann) to construct target molecules |
| Organic Synthesis | Fluorinated functionalized arene building block for materials and fine chemical development | Enables introduction of additional functional groups either via nitro reduction to aniline followed by diazotization-substitution, or directly through nucleophilic aromatic substitution (SNAr) |
Manufacturing Quality Control of 4-(Difluoromethoxy)nitrobenzene
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase HPLC with UV detection at 254 nm, based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient HPLC-UV; identification via retention time matching and threshold-based reporting. |
| Residual Solvents | GC-FID | Separates and quantifies volatile organic solvents (e.g., methanol, acetone) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration using iodine generation and stoichiometric reaction with water. |
| Heavy Metals | ICP-OES | Measures total elemental metal content (e.g., Pb, Cd, Ni) after acid digestion by inductively coupled plasma optical emission spectrometry. |
| Chloride Impurity | Ion Chromatography | Quantifies chloride ions using suppressed conductivity detection after anion exchange separation. |
| Sulfated Ash | Gravimetric Analysis | Measures inorganic residue after controlled combustion of sample with sulfuric acid treatment and high-temperature incineration. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range at which solid transitions to liquid, indicating crystallinity and presence of impurities. |
| Appearance | Visual Inspection | Assesses physical state, color, and clarity of solid material against established visual standards under controlled lighting. |
| Particle Size Distribution | Laser Diffraction | Measures size distribution of solid particles in suspension using angular scattering pattern analysis of laser light. |
| Organic Volatile Impurities (OVI) | GC-MS | Identifies and quantifies unknown or non-target volatile organic impurities using gas chromatography coupled with mass spectrometric detection. |
| pH of Aqueous Suspension | pH Meter | Measures hydrogen ion activity in a defined suspension of the compound in water using calibrated glass electrode. |
Technical Specifications of 4-(Difluoromethoxy)nitrobenzene
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Melting Point | 74–78°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-(Difluoromethoxy)nitrobenzene
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-(Difluoromethoxy)nitrobenzene
Safety Information of 4-(Difluoromethoxy)nitrobenzene
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-(Difluoromethoxy)nitrobenzene
Industrial 4-(Difluoromethoxy)nitrobenzene Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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