Fmoc-L-Arg(Pbf)-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 154445-77-9 |
| Product name | Fmoc-L-Arg(Pbf)-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for Fmoc-L-Arg(Pbf)-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk Fmoc-L-Arg(Pbf)-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of Fmoc-L-Arg(Pbf)-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | As a protected amino acid monomer in peptide synthesis for preparing arginine-containing therapeutic peptides (e.g., anticoagulant peptides, hormonal drugs) | Solid-phase peptide synthesis (SPPS) using the Fmoc strategy to incorporate arginine residues; the guanidino group is protected with the Pbf group to prevent side reactions |
| Biotechnology | For synthesizing cell-penetrating peptides (CPPs), antimicrobial peptides, and custom peptide sequences in protein engineering research | Sequence-specific coupling on automated peptide synthesizers, followed by TFA-mediated cleavage to remove Pbf and Fmoc protecting groups |
| Research | As a standard reagent for developing peptide chemistry methodologies, optimizing protecting groups, and conducting structure–activity relationship (SAR) studies | Manual or automated solid-phase synthesis employing coupling reagents such as HBTU/HOBt for amide bond formation |
Manufacturing Quality Control of Fmoc-L-Arg(Pbf)-OH
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample color and physical state (typically white to off-white crystalline powder) for any foreign particles or agglomeration. |
| Identification | Fourier Transform Infrared Spectroscopy (FT-IR) | Confirm characteristic functional groups (e.g., Fmoc group, carboxyl group, Pbf protecting group) by comparing the infrared absorption spectrum with a reference standard spectrum. |
| Proton Nuclear Magnetic Resonance Spectroscopy (¹H NMR) | Determine the molecular structure and integrity of protecting groups by measuring the proton spectrum in deuterated solvents. | |
| Assay | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (typically at 210–220 nm) and external standard or area normalization method to determine the content of the main component. |
| Related Substances (Impurities) | High-Performance Liquid Chromatography (HPLC) | Under the same conditions as above, detect and quantify process-related impurities and degradation products (e.g., deprotected products, dimers); typically require individual impurity ≤0.5% and total impurities ≤1.0%. |
| Specific Rotation | Polarimetry | Prepare a solution of a specified concentration (e.g., 1% in DMF) and measure the optical rotation at a specified wavelength (typically sodium D line, 589 nm) to verify optical purity. |
| Water Content | Karl Fischer Titration | Determine water content in the sample using volumetric or coulometric methods; typically require ≤1.0%. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection to detect residual organic solvents (e.g., DCM, DMF, methanol) retained during synthesis or purification, in compliance with ICH Q3C limits. |
| Heavy Metals | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) |
Determine the total content of heavy metal elements such as lead, cadmium, mercury, and arsenic; typically require ≤10 ppm. |
| pH (Solution) | pH Meter Method | Prepare a solution of a specified concentration (in water or an appropriate solvent) and measure the pH value as an auxiliary quality indicator. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range of the sample as a physical constant reference (Fmoc-Pbf-Arg-OH typically does not exhibit a distinct melting point and may decompose). |
Technical Specifications of Fmoc-L-Arg(Pbf)-OH
| Test Item | Specification |
|---|---|
| Appearance | White to almost white powder or crystals |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | -6.5 to -4.5 deg (c=1, in 1% Acetic Acid/DMF) |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of Fmoc-L-Arg(Pbf)-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of Fmoc-L-Arg(Pbf)-OH
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Industrial Fmoc-L-Arg(Pbf)-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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