China Factory Direct
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| CAS number | 1546-79-8 |
| Product name | 1-(Trifluoroacetyl)imidazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent GradeIndustrial Grade |
| Packaging | 25L/drum200L/drum1000L/IBC |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | As a trifluoroacetylating reagent for synthesizing pharmaceutical intermediates or protecting amino groups | Reacts with amino compounds in organic synthesis to introduce the trifluoroacetyl group |
| Organic Synthesis | For preparing trifluoromethyl-containing heterocyclic compounds | Acts as an active acylating agent in modification reactions of imidazole rings or other heterocycles |
| Materials Science | Monomer or modifier for synthesizing fluorinated polymers | Introduces the trifluoroacetyl group via polymerization or grafting reactions |
| Agrochemicals | Intermediate in the production of fluorinated pesticides | Reacts with other pesticide precursors to construct trifluoroacetyl-functional structures |
| Analytical Chemistry | Derivatization reagent to enhance detection sensitivity in chromatography or mass spectrometry | Reacts with target molecules to generate derivatives exhibiting stronger signal response |
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Purity | Gas Chromatography (GC) | Separation of 1-(trifluoroacetyl)imidazole using gas chromatography, with quantification via peak area normalization or external standard method to evaluate the content of the main component and impurity levels. Typically, capillary columns (e.g., DB-5, HP-5) and FID detectors are used. |
| Assay | High-Performance Liquid Chromatography (HPLC) | Utilizes a reversed-phase C18 column with mobile phases such as methanol/water or acetonitrile/water, detected by a UV detector (e.g., 210–230 nm). Quantification is performed via external or internal standard method, suitable for thermally unstable or non-volatile samples. |
| Water Content | Karl Fischer Titration | Utilizes volumetric or coulometric Karl Fischer titration, offering high specificity and sensitivity for precise determination of trace water content, particularly critical for acylating reagents. |
| Residual Solvents | Headspace Gas Chromatography (HS-GC) | Detection of possible residual organic solvents (e.g., dichloromethane, acetonitrile, toluene) from the manufacturing process via headspace sampling combined with gas chromatography (FID detector), in compliance with ICH Q3C guidelines. |
| Inorganic Impurities (Ash/Metal Ions) | Inductively Coupled Plasma Mass Spectrometry (ICP-MS) or Atomic Absorption Spectroscopy (AAS) | After acid digestion of the sample, ICP-MS or AAS is employed to determine residual inorganic elements such as sodium, potassium, iron, and heavy metals, ensuring compliance with pharmacopeial or customer specifications for metal impurities. |
| pH (if prepared as a solution) | pH Meter Method | The sample is dissolved in an appropriate solvent (e.g., water or dilute alcohol), and its acidity or alkalinity is measured using a calibrated pH meter, indirectly reflecting hydrolysis or side-reaction conditions. |
| Appearance and Color | Visual Color Comparison | Under specified conditions, observe the sample’s appearance (should be colorless to pale yellow liquid) and clarity; if necessary, compare with standard color solutions to determine whether degradation or colored impurities are present. |
| Test Item | Specification |
|---|---|
| Appearance | Colorless liquid |
| Purity | >=98.0% (GC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Identification (NMR) | Consistent with structure |
| Identification (IR) | Consistent with structure |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.