Carbamic acid, (3-hydroxycyclobutyl)-, 1,1-dimethylethyl ester (9CI) Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 154748-63-7 |
| Product name | Carbamic acid, (3-hydroxycyclobutyl)-, 1,1-dimethylethyl ester (9CI) |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 154748-63-7
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 154748-63-7 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 154748-63-7
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Serves as a synthetic intermediate for constructing drug molecules containing a cyclobutylamine moiety | Participates in the synthesis of active compounds via deprotection, coupling, or cyclization reactions |
| Organic Synthesis | Used as a chiral building block or as a reagent for amino group protection | Introduces the tert-butoxycarbonyl (Boc) protecting group in multistep syntheses to facilitate subsequent functional group transformations |
| Medicinal Chemistry | Applied in the development of protease inhibitors or GPCR-targeted compounds | Functions as a rigid cyclic amine structural unit to enhance conformational constraint and target binding affinity |
Manufacturing Quality Control of 154748-63-7
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component by UV absorbance at specific wavelength using reverse-phase chromatography with external standard calibration. |
| Related Substances | HPLC-UV | Detects and quantifies structurally similar impurities using gradient reverse-phase HPLC with UV detection. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., THF, DMF, EtOAc) by gas chromatography with flame ionization detection. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration based on iodine consumption in pyridine-methanol medium. |
| Optical Rotation | [alpha]D Measurement | Measures specific rotation of chiral compound using sodium D-line light in solution to confirm enantiomeric identity and purity. |
| Residual Metals (e.g., Pd, Ni, Fe) | ICP-MS | Quantifies trace metal catalyst residues by inductively coupled plasma mass spectrometry after acid digestion. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residual tert-Butyl Carbamate (Boc-OH) | HPLC-UV | Detects unreacted Boc protecting group derivative by reverse-phase HPLC with UV detection. |
| Heavy Metals (General) | USP <231> Sulfide Precipitation | Semi-quantitative limit test for heavy metals (Pb, Hg, Cd, As) based on colorimetric comparison after sulfide precipitation. |
| Melting Point | Capillary Melting Point Apparatus | Determines temperature range of solid-to-liquid transition using calibrated capillary apparatus per USP <741>. |
| Loss on Drying | Gravimetric (105 C, 2 h) | Measures volatile content by weight loss after drying under controlled temperature and time. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in a saturated aqueous suspension using calibrated glass electrode. |
Technical Specifications of 154748-63-7
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Optical Rotation | -15.0 to -19.0° (c=1, in methanol) |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 154748-63-7
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 154748-63-7
Packaging of 154748-63-7
Industrial 154748-63-7 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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