4-Chloro-2,6-dimethyl-3-nitropyridine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 15513-48-1 |
| Product name | 4-Chloro-2,6-dimethyl-3-nitropyridine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Chloro-2,6-dimethyl-3-nitropyridine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Chloro-2,6-dimethyl-3-nitropyridine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Chloro-2,6-dimethyl-3-nitropyridine
| Industry | Application | Process |
|---|---|---|
| Pesticides | Intermediate for synthesizing novel pyridine-based insecticides and fungicides | Prepared via nitration and chlorination; serves as a key intermediate in subsequent coupling or substitution reactions |
| Pharmaceuticals | Heterocyclic scaffold for antiviral or antitumor drug synthesis | Used as a nitrogen-containing heterocyclic precursor; the core drug structure is constructed through reduction, amination, and related steps |
| Dyes & Pigments | Intermediate for synthesizing specialty nitrogen-containing heterocyclic dyes | Chromophore groups are introduced via nucleophilic substitution or coupling reactions for high-stability dye synthesis |
Manufacturing Quality Control of 4-Chloro-2,6-dimethyl-3-nitropyridine
| Test Item | Common Testing Methods | Method Overview |
|---|---|---|
| Appearance and Physical Form | Visual Inspection, Melting Point Determination | Observe sample color and state (typically yellow to orange crystalline powder), determine melting point range (literature value approximately 110–115°C) to assess purity and crystallinity. |
| Assay (Active Ingredient) | High-Performance Liquid Chromatography (HPLC) | Use a C18 column with methanol/water or acetonitrile/water as mobile phase; detect using UV detector (λ=254–310 nm); quantify active ingredient by external standard method. Offers high accuracy and good reproducibility. |
| Impurity Profile Analysis | HPLC-UV / HPLC-MS | Separate potential organic impurities (e.g., unreacted starting materials, by-products, degradation products) via gradient elution; identify structures using mass spectrometry (MS). Control individual and total impurities ≤0.5%. |
| Nitro Group Confirmation | Fourier Transform Infrared Spectroscopy (FT-IR) | Detect characteristic absorption peaks: nitro group (–NO₂) shows strong absorptions near 1530 cm⁻¹ and 1350 cm⁻¹, used for qualitative confirmation of functional groups. |
| Chlorine Content | Combustion Ion Chromatography (CIC) or Oxygen Bomb Combustion + Ion Chromatography | Sample is combusted in an oxygen bomb to convert chlorine into chloride ions, followed by quantitative determination using ion chromatography. Ensure chlorine content matches theoretical value (theoretical Cl% ≈ 23.5%). |
| Residual Solvents | Gas Chromatography (GC) | Use DB-624 or HP-INNOWAX column with FID detector to analyze residual solvents (e.g., DMF, ethanol, ethyl acetate), complying with ICH Q3C guidelines. |
| Moisture Content | Karl Fischer Titration | Electrochemical method for precise measurement of trace moisture; control moisture content ≤0.5% to prevent hydrolysis or stability issues during storage. |
| Melting Point | Capillary Melting Point Apparatus | Determine melting point range as an auxiliary indicator of purity; compare with literature values to detect possible impurities. |
| Heavy Metal Residues | Atomic Absorption Spectroscopy (AAS) or Inductively Coupled Plasma Mass Spectrometry (ICP-MS) | Test for heavy metals such as Pb, Cd, Hg, As according to pharmacopoeial methods (e.g., USP <231>); typical acceptance limit ≤10 ppm. |
| Particle Size Distribution (if applicable) | Laser Diffraction Method | For powdered raw materials, measure particle size distribution to ensure uniformity in downstream processes (e.g., formulation blending). |
| Polymorphic Form Analysis (if applicable) | X-Ray Powder Diffraction (XRPD) | Used to confirm crystal structure and consistency of polymorphic form, avoiding variations in solubility and stability due to polymorphism. |
Technical Specifications of 4-Chloro-2,6-dimethyl-3-nitropyridine
| Test Item | Specification |
|---|---|
| Appearance | White to light yellow crystalline powder |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Melting Point | 128–132°C |
| Water Content (KF) | <=0.5% |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Chloro-2,6-dimethyl-3-nitropyridine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Chloro-2,6-dimethyl-3-nitropyridine
Safety Information of 4-Chloro-2,6-dimethyl-3-nitropyridine
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Chloro-2,6-dimethyl-3-nitropyridine
Industrial 4-Chloro-2,6-dimethyl-3-nitropyridine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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