China Factory Direct
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| CAS number | 156-83-2 |
| Product name | 4-Chloro-2,6-diaminopyrimidine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty GradeElectronic GradeIndustrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pesticides | Synthesis of herbicide intermediates | Prepared via reaction of chloropyrimidine with aqueous ammonia, followed by amination and substitution steps |
| Pharmaceuticals | Synthesis of antiviral drugs and antibiotic intermediates | Serves as a pyrimidine scaffold in drug molecule construction, commonly employed in nucleoside analog synthesis |
| Polymers | Organic synthesis intermediate | Used to produce functional polymeric materials, such as thermal stabilizers or crosslinking agents |
| Fine chemicals | Dye and pigment intermediates | Participates in the synthesis of azo dyes or heterocyclic dyes to enhance dye performance and stability |
| Electronic chemicals | Additive for semiconductor materials | Applied to improve the electrical properties of semiconductor materials, functioning as a dopant or passivation agent |
| Test Item | Common Test Method | Method Overview |
|---|---|---|
| Purity Analysis | High-Performance Liquid Chromatography (HPLC) | Uses a reversed-phase C18 column with methanol/water or acetonitrile/water as the mobile phase, and UV detection (typically at 254 nm). The main component is quantified by comparing retention times with reference standards, enabling accurate determination of purity and impurity levels. |
| Impurity Detection | Liquid Chromatography-Mass Spectrometry (LC-MS) | Combines the separation capability of HPLC with the high sensitivity and structural identification power of mass spectrometry. Suitable for qualitative and quantitative analysis of trace impurities (e.g., synthesis by-products, isomers) in complex matrices. |
| Assay (Content Determination) | Ultraviolet-Visible Spectrophotometry (UV-Vis) | Quantifies based on the characteristic absorption peak of 2,4-diamino-6-chloropyrimidine at specific wavelengths (e.g., 250–270 nm) using a calibration curve. Simple and fast, suitable for rapid screening, but susceptible to interference from co-existing substances. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Both ¹H NMR and ¹³C NMR provide detailed molecular structural information, confirming whether the chemical structure is correct. A key technique for verifying compound identity, commonly used during research and development or reference standard preparation. |
| Molecular Weight and Formula Identification | Mass Spectrometry (MS) | Utilizes ionization techniques such as Electrospray Ionization (ESI) or Electron Impact Ionization (EI) to obtain precise molecular ion peaks (e.g., m/z 169.0 for [M+H]⁺). Combined with isotope pattern analysis, it confirms molecular formula and molecular weight. |
| Thermal Stability Analysis | Differential Scanning Calorimetry (DSC) | Measures thermal effects during heating to determine thermal properties such as melting point and decomposition temperature, aiding in assessing product stability and optimal storage conditions. |
| Polymorph Analysis | X-Ray Diffraction (XRD) | Used to distinguish between different crystalline forms (e.g., amorphous vs. crystalline), which is critical for ensuring consistency in raw materials or intermediates. Particularly important in formulation development to maintain stable polymorphic form. |
| Test Item | Specification |
|---|---|
| Appearance | Pale-yellow solid |
| Purity | >=98.5% (HPLC) |
| Melting Point | 204–208°C |
| Total Impurities | <=1.5% (HPLC) |
| Single Impurity | <=0.5% (HPLC) |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
| Pictograms | ![]() |
| Signal Word | Warning |
| Safety Data Sheet | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.