6-AMINO-5-CHLORO-NICOTINONITRILE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 156361-02-3 |
| Product name | 6-AMINO-5-CHLORO-NICOTINONITRILE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 6-AMINO-5-CHLORO-NICOTINONITRILE
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 6-AMINO-5-CHLORO-NICOTINONITRILE Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 6-AMINO-5-CHLORO-NICOTINONITRILE
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate in the synthesis of antitumor agents (e.g., crizotinib analogues) | Participates in multistep synthetic routes via nucleophilic substitution, coupling reactions, and related transformations |
| Agrochemicals | Structural building block for novel high-efficiency insecticides or herbicides | Serves as a core scaffold in heterocycle construction and functional group interconversion |
| Chemical Research | Organic synthesis building block for constructing nitrogen-containing heterocyclic compound libraries | Employed in transition metal-catalyzed coupling reactions, including Suzuki and Buchwald–Hartwig couplings |
| Materials Science | Precursor with potential application in optoelectronic materials or ligand design | Further derivatized via cyano or amino functional groups to construct functional molecules |
Manufacturing Quality Control of 6-AMINO-5-CHLORO-NICOTINONITRILE
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification via reverse-phase HPLC with UV detection at 254 nm using external standard calibration. |
| Related Substances | HPLC-DAD | Separation and identification of impurities using gradient HPLC with diode-array detection and reference standards. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify volatile organic solvents based on USP <467>. |
| Water Content | Karl Fischer Titration | Volumetric titration with iodine-based reagent to determine trace water content in non-aqueous matrix. |
| Heavy Metals | ICP-MS | Multi-element quantification of Pb, Cd, Hg, As, and other heavy metals after acid digestion and dilution. |
| Chloride Content | Potentiometric Titration | Titration with silver nitrate using silver indicator electrode to measure inorganic chloride impurities. |
| Residue on Ignition | Gravimetric Analysis | Weighing residue after high-temperature ashing to assess inorganic ash content per USP <281>. |
| Particle Size Distribution | Laser Diffraction | Measurement of dry powder particle size distribution using Mie scattering theory and calibrated instrument. |
| Melting Point | Capillary Melting Point Apparatus | Determination of solid-to-liquid transition temperature range using calibrated capillary method per USP <741>. |
| pH of Aqueous Suspension | pH Meter | Measurement of pH in a defined suspension (e.g., 1% w/v in water) using calibrated glass electrode. |
| Bulk Density | ASTM D1895 | Determination of mass per unit volume for free-flowing powder using standardized graduated cylinder and tapping procedure. |
| Microbial Limits | Membrane Filtration | Quantification of aerobic bacteria, yeasts, and molds by filtration, membrane transfer, and incubation on selective media. |
Technical Specifications of 6-AMINO-5-CHLORO-NICOTINONITRILE
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.5% (LC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.3% |
| Water Content (KF) | <=0.5% |
| Melting Point | 142–146°C |
| Identification (NMR) | Conforms to reference spectrum |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 6-AMINO-5-CHLORO-NICOTINONITRILE
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 6-AMINO-5-CHLORO-NICOTINONITRILE
Safety Information of 6-AMINO-5-CHLORO-NICOTINONITRILE
| Pictograms |   |
| Signal Word | Danger |
| Safety Data Sheet | |
Packaging of 6-AMINO-5-CHLORO-NICOTINONITRILE
Industrial 6-AMINO-5-CHLORO-NICOTINONITRILE Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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