4-Boc-1-piperazineacetic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 156478-71-6 |
| Product name | 4-Boc-1-piperazineacetic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeReagent Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Boc-1-piperazineacetic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Boc-1-piperazineacetic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Boc-1-piperazineacetic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing protease inhibitors and antiviral agents | Used as a key building block in solid-phase peptide synthesis or solution-phase coupling reactions, via condensation of Boc-protected piperazineacetic acid with amino acids or amines |
| Pharmaceuticals | Structural module for synthesizing HIV protease inhibitors | After deprotection (TFA-mediated Boc removal), the piperazineacetic acid moiety is introduced via reaction with acyl chlorides or activated esters in multistep organic synthesis |
| Pharmaceuticals | Construction of biologically active molecules containing a piperazine ring | Applied as a pharmacophore precursor; modified through amidation, alkylation, or cyclization to optimize pharmacokinetic properties |
| Chemical R&D | Chiral or achiral nitrogen-containing heterocyclic building block for organic synthesis | Employed to construct compound libraries based on the piperazine-acetic acid scaffold, supporting drug screening and structure–activity relationship studies |
Manufacturing Quality Control of 4-Boc-1-piperazineacetic acid
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reverse-phase chromatography with UV detection at 210 nm based on peak area comparison against reference standard. |
| Related Substances | HPLC-UV | Detects and quantifies structurally related impurities using gradient elution and UV detection, relative to main peak response. |
| Residual Solvents | GC-FID | Measures volatile organic solvents (e.g., DMF, THF, ethyl acetate) by gas chromatography with flame ionization detection using headspace sampling. |
| Water Content | Karl Fischer Titration | Determines trace water via coulometric or volumetric titration with iodine-based reagent reacting stoichiometrically with water. |
| Heavy Metals | ICP-MS | Quantifies elemental impurities (e.g., Pb, Cd, Ni, Fe) after acid digestion using inductively coupled plasma mass spectrometry. |
| Chloride Content | Ion Chromatography | Separates and quantifies chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measures inorganic ash content by ignition at 700-800 C followed by weighing of residual non-volatile matter. |
| Optical Rotation | Polarimetry | Determines specific rotation using sodium D-line light to confirm chiral integrity and enantiomeric purity. |
| Melting Point | Capillary Melting Point Apparatus | Measures temperature range of solid-to-liquid transition to verify identity and crystallinity. |
| Particle Size Distribution | Laser Diffraction | Analyzes dry or wet dispersed sample to determine volume-weighted particle size distribution. |
| pH (1% w/v aqueous suspension) | pH Meter | Measures hydrogen ion activity in aqueous suspension to assess acid-base character and hydrolytic stability. |
| Microbial Limits | Membrane Filtration | Quantifies aerobic mesophilic microorganisms and detects specified pathogens using selective culture media and incubation. |
Technical Specifications of 4-Boc-1-piperazineacetic acid
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.0% (GC-MS) |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 125–129 °C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Boc-1-piperazineacetic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Boc-1-piperazineacetic acid
Safety Information of 4-Boc-1-piperazineacetic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-Boc-1-piperazineacetic acid
Industrial 4-Boc-1-piperazineacetic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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