3,5-Difluorophenylboronic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 156545-07-2 |
| Product name | 3,5-Difluorophenylboronic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Agricultural GradeMaterial GradeSpecialty GradeReagent Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 3,5-Difluorophenylboronic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 3,5-Difluorophenylboronic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 3,5-Difluorophenylboronic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Synthesis of fluorinated pharmaceutical intermediates | Used as the boronic acid component in Suzuki-Miyaura cross-coupling reactions with haloarenes under palladium catalysis to construct C–C bonds for antitumor, antiviral, or central nervous system drugs |
| Agrochemicals | Synthesis of novel fluorinated fungicides/insecticides | Participates in cross-coupling reactions to construct fluorinated phenyl ring structures for synthesizing aryl heterocyclic compounds with high biological activity |
| Materials Science | Synthesis of organic light-emitting materials (OLEDs) | Used as a precursor in coupling reactions to synthesize conjugated polymers or small-molecule emissive layer materials exhibiting thermal stability and high luminescence efficiency |
| Chemical Reagents | Organic synthesis intermediate | Used to construct complex aromatic systems; serves as a highly selective boronic acid reagent in transition metal-catalyzed coupling reactions, widely applied in laboratory-scale fine chemical synthesis |
Manufacturing Quality Control of 3,5-Difluorophenylboronic acid
| Test Item | Common Testing Method | Method Overview |
|---|---|---|
| Appearance | Visual Inspection | Observe the sample's color, physical state (e.g., white to off-white crystalline powder), and presence of visible impurities. |
| Purity | High-Performance Liquid Chromatography (HPLC) | Use a reversed-phase C18 column with a UV detector (typically around 254 nm). Identify components by retention time and quantify purity using peak area normalization or external standard method. |
| Assay | Titration (e.g., alkalimetric titration) | The boronic acid group forms a complex with polyols (e.g., mannitol), releasing hydrogen ions, which are then titrated with standardized NaOH solution to determine active content. |
| Structural Confirmation | Nuclear Magnetic Resonance Spectroscopy (NMR) | Use ¹H NMR, ¹³C NMR, and ¹⁹F NMR to confirm molecular structure, verifying correct substitution patterns of fluorine atoms and aromatic rings. |
| Moisture Content | Karl Fischer Titration | Apply electrochemical titration principle for precise determination of moisture content in samples; suitable for trace water detection. |
| Residual Solvents | Gas Chromatography (GC) | Detect potential residual solvents from manufacturing processes (e.g., toluene, ethanol, tetrahydrofuran) by GC to ensure compliance with ICH permissible limits. |
| Melting Point | Melting Point Apparatus | Determine the melting temperature range using an automatic or manual melting point instrument; used as a preliminary indicator of substance purity and consistency. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | Measure residual levels of toxic elements such as lead, mercury, cadmium, and arsenic to ensure compliance with pharmaceutical or electronic-grade material safety standards. |
| Individual Impurity / Related Substances | HPLC or UPLC | Use high-resolution chromatographic methods to detect possible synthesis intermediates, by-products, or degradation products; calculate individual impurity levels and assess total impurity profile. |
| Sulfated Ash (Residue on Ignition) | Gravimetric Method | Char the sample at high temperature, treat with sulfuric acid, then ignite to constant weight to measure the amount of non-volatile inorganic residue. |
Technical Specifications of 3,5-Difluorophenylboronic acid
| Test Item | Specification |
|---|---|
| Appearance | Off-white crystalline solid |
| Purity | >=98.0% (by LC-MS) |
| Melting Point | 142–146 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=10 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 3,5-Difluorophenylboronic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 3,5-Difluorophenylboronic acid
Safety Information of 3,5-Difluorophenylboronic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 3,5-Difluorophenylboronic acid
Industrial 3,5-Difluorophenylboronic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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