D(-)-Arginine Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 157-06-2 |
| Product name | D(-)-Arginine |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeFood GradeCosmetic Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for D(-)-Arginine
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk D(-)-Arginine Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of D(-)-Arginine
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Chiral drug intermediates for synthesis of antithrombotic, antitumor, and immunomodulatory agents | Optically pure D-arginine is prepared via chiral resolution or enzymatic synthesis and used as a key chiral building block in peptide coupling or prodrug modification |
| Food | Nutritional fortificant and flavor enhancer (approved for use in specific countries only) | Incorporated into foods for special medical purposes or sports nutrition supplements via dry powder blending or solution homogenization |
| Cosmetics | Skin conditioning agent that promotes collagen synthesis and wound healing | Formulated at 0.1–0.5% concentration into aqueous or polyol-based systems (e.g., emulsions, serums) using low-temperature homogenization |
| Biotechnology | Cell culture additive to enhance growth and antibody expression in mammalian cells (e.g., CHO) | Dissolved in serum-free medium to a final concentration of 0.2–2.0 mM, sterilized by 0.22 μm filtration, and added to perfusion or fed-batch culture systems |
Manufacturing Quality Control of D(-)-Arginine
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (D-Arginine Content) | Acid-Base Titration with HCl | Quantitative neutralization of the amino group using standardized hydrochloric acid solution and potentiometric or indicator endpoint detection. |
| Optical Rotation | [alpha]D Measurement | Measurement of the rotation of plane-polarized light at 20 degrees C using a sodium D-line source to confirm chiral purity and identity. |
| Loss on Drying | Gravimetric Analysis (Thermogravimetry) | Determination of volatile content by measuring mass loss after drying at 105 degrees C under controlled conditions. |
| Residue on Ignition | Weight Loss on Ignition | Conversion of organic material to CO2 and H2O by high-temperature ashing, followed by weighing of inorganic residue. |
| Chloride Impurity | Argentometric Titration (Mohr Method) | Precipitation titration with standardized silver nitrate solution using potassium chromate as indicator for chloride ion quantification. |
| Sulfate Impurity | Barium Sulfate Gravimetry | Precipitation of sulfate as barium sulfate under acidic conditions and gravimetric determination of the dried precipitate. |
| Heavy Metals (as Pb) | Colorimetric Sulfide Precipitation | Reaction with thioacetamide in acidic medium to form colored metal sulfide complexes, compared against lead standard. |
| Iron Impurity | UV-Vis Spectrophotometry (1,10-Phenanthroline) | Formation of orange-red ferroin complex measured at ~510 nm after reduction of Fe3+ to Fe2+. |
| Related Substances | HPLC with UV Detection | Separation of structurally similar impurities (e.g., L-arginine, arginine derivatives) on a reversed-phase column with UV detection at 200-220 nm. |
| Water Content | Karl Fischer Coulometric Titration | Electrochemical generation of iodine to react stoichiometrically with water, measuring charge required for complete reaction. |
| pH of Aqueous Solution | Potentiometric pH Measurement | Determination of hydrogen ion activity in a 1% w/v aqueous solution using calibrated glass electrode system. |
| Microbial Limits | Membrane Filtration and Plate Count | Quantitative recovery of viable aerobic microorganisms from sample solution via filtration, followed by incubation on nutrient agar and colony enumeration. |
Technical Specifications of D(-)-Arginine
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (by NMR) |
| Water Content (KF) | <=0.5% |
| Melting Point | 222-225°C |
| Optical Rotation | -24.0 to -28.0° (c=1, 1M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
| Heavy Metals | <=10 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of D(-)-Arginine
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of D(-)-Arginine
Packaging of D(-)-Arginine
Industrial D(-)-Arginine Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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