(E)-TERT-BUTYL 3-((DIMETHYLAMINO)METHYLENE)-4-OXOPYRROLIDINE-1-CARBOXYLATE Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 157327-42-9 |
| Product name | (E)-TERT-BUTYL 3-((DIMETHYLAMINO)METHYLENE)-4-OXOPYRROLIDINE-1-CARBOXYLATE |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 157327-42-9
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 157327-42-9 Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 157327-42-9
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Intermediate for pyrrolidinone-based pharmaceuticals | Used as a stoichiometric nucleophilic reagent to introduce carbon atoms at the α-position of the pyrrolidinone scaffold, enabling synthesis of α-substituted pyrrolidinone derivatives |
| Pharmaceutical Chemicals | Synthesis of neuroactive pharmaceuticals | Applied in the synthesis of 2-pyrrolidinone compounds exhibiting neuroprotective and antiepileptic activity (e.g., structural analogues of levetiracetam) |
| Pharmaceutical Chemicals | Synthesis of chiral pharmaceuticals | Employed to construct chiral pyrrolidinone scaffolds, followed by asymmetric transformations to produce chiral pharmaceutical intermediates |
| Pharmaceutical Chemicals | Functionalization reagent | Serves as a reactive enaminoketone intermediate in electrophilic substitution reactions to introduce specific functional groups |
Manufacturing Quality Control of 157327-42-9
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification using reverse-phase HPLC with UV detection at 210-230 nm, comparing peak area to a certified reference standard. |
| Related Substances | HPLC-DAD | Separation and detection of impurities using gradient HPLC with diode-array detection; identification and quantification based on retention time and spectral match. |
| Residual Solvents | GC-FID | Determination of volatile organic solvents (e.g., methanol, ethyl acetate, toluene) by gas chromatography with flame ionization detection against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to quantify water via stoichiometric reaction in anhydrous methanol medium. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification of heavy metals (Pb, Cd, Cr, Ni, As) after acid digestion, using inductively coupled plasma optical emission spectrometry. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Residue on Ignition | Gravimetric Analysis | Measurement of inorganic ash content by ignition at 700-800 C followed by precise weighing of residual residue. |
| Melting Point | Capillary Melting Point Apparatus | Determination of temperature range at which solid transitions to liquid, using calibrated capillary apparatus per USP <741>. |
| Optical Rotation | Polarimetry | Measurement of specific rotation using sodium D-line light source to assess chiral purity and identity. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry or wet dispersed sample to determine volume-weighted particle size distribution based on light scattering patterns. |
| Bulk Density | Tap Density Tester | Measurement of mass per unit volume after controlled tapping of a known mass in a graduated cylinder per USP <616>. |
| Microbial Limits | Membrane Filtration + Culture | Enumeration of aerobic microorganisms and detection of specified pathogens (e.g., E. coli, S. aureus) by filtration, membrane transfer, and incubation on selective media. |
Technical Specifications of 157327-42-9
| Test Item | Specification |
|---|---|
| Appearance | Yellow solid |
| Purity | >=98.5% (GC-MS) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Melting Point | 128–132°C |
| Identification (NMR) | Conforms to reference standard |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 157327-42-9
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 157327-42-9
Packaging of 157327-42-9
Industrial 157327-42-9 Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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