China Factory Direct
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| CAS number | 157355-79-8 |
| Product name | FMOC-D-HIS-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeMaterial GradeSpecialty Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Synthesis | Used as an amino acid protecting group in the synthesis of peptide-based drugs | Introduced into the peptide chain via condensation reactions during solid-phase or solution-phase peptide synthesis |
| Biochemical Research | Synthesis of structurally defined peptides and protein fragments | Prepared via organic synthesis to incorporate D-histidine into peptides for studying biological activity and structure–function relationships |
| Advanced Materials | Used in the preparation of bio-based materials with specialized functionalities | Incorporated into polymeric materials via polymerization or crosslinking reactions to enhance material performance |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination using reverse-phase HPLC with UV detection at 265 nm, comparing peak area against a certified reference standard. |
| Related Substances | HPLC-UV | Separation and quantification of impurities using gradient HPLC-UV; identification based on retention time matching and threshold limits per ICH Q3B. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify residual solvents (e.g., DMF, DCM, methanol) against calibrated standards. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration using iodine-based reagent to determine trace water content via stoichiometric reaction. |
| Optical Rotation | [alpha]D Measurement | Measurement of specific optical rotation using a polarimeter at 20 °C and sodium D-line (589 nm) to confirm chiral integrity. |
| Heavy Metals | ICP-MS | Quantification of toxic elements (Pb, Cd, Hg, As) by inductively coupled plasma mass spectrometry after acid digestion. |
| Residual Palladium | ICP-MS | Specific detection of Pd residues from coupling reactions using ICP-MS with collision/reaction cell for interference removal. |
| Chloride Content | Ion Chromatography | Separation and quantification of chloride ions using suppressed conductivity detection after aqueous extraction. |
| Loss on Drying | Gravimetric Analysis | Mass loss measured after drying under controlled temperature/vacuum conditions to determine volatile content. |
| pH (1% w/v solution) | Potentiometric pH Measurement | Determination of aqueous solution acidity/basicity using calibrated pH electrode in deionized water. |
| Particle Size Distribution | Laser Diffraction | Analysis of dry powder particle size distribution via light scattering pattern generated by dispersed sample in air. |
| Microbial Limits | Membrane Filtration | Quantitative assessment of aerobic microorganisms and absence of specified pathogens using culture-based membrane filtration and incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Purity | >=98.5% |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Melting Point | 245-249°C |
| Optical Rotation | -20.0 to -24.0° (c=1, DMF) |
| Heavy Metals | <=20 ppm |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.