FMOC-D-THR-OH Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 157355-81-2 |
| Product name | FMOC-D-THR-OH |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for FMOC-D-THR-OH
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk FMOC-D-THR-OH Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of FMOC-D-THR-OH
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical R&D | Peptide synthesis intermediate | Used as a protected amino acid in solid-phase or solution-phase peptide synthesis to incorporate D-threonine residues via Fmoc strategy |
| Biotechnology | Protein engineering and modification | Applied in the design and synthesis of biologically active peptides containing D-threonine to enhance metabolic stability |
| Organic synthesis | Chiral molecule construction | Employed as a chiral building block in asymmetric synthesis for constructing complex natural products or pharmaceutical molecules |
Manufacturing Quality Control of FMOC-D-THR-OH
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantifies main component using reversed-phase HPLC with UV detection at 265 nm, comparing peak area to a certified reference standard. |
| Chiral Purity | Chiral HPLC | Separates D- and L-enantiomers on a chiral stationary phase; enantiomeric excess calculated from peak area ratio. |
| Water Content | Karl Fischer Titration | Measures water by coulometric or volumetric titration using iodine-based reagent; based on stoichiometric reaction with water. |
| Residual Solvents | GC-FID | Detects and quantifies residual solvents (e.g., DMF, DCM, methanol) using gas chromatography with flame ionization detection. |
| Heavy Metals | ICP-MS | Quantifies trace metal impurities (e.g., Pb, Cd, Ni, Fe) via inductively coupled plasma mass spectrometry after acid digestion. |
| Residue on Ignition | Gravimetric Analysis | Measures non-volatile inorganic residue after high-temperature ashing (700-800 C) and weighing. |
| Specific Optical Rotation | Polarimetry | Determines optical activity using sodium D-line light; rotation angle correlates with enantiomeric composition and concentration. |
| pH of Solution | Potentiometric pH Measurement | Measures hydrogen ion activity in aqueous suspension or solution using calibrated glass electrode and pH meter. |
| Particle Size Distribution | Laser Diffraction | Analyzes particle size by measuring angular variation in laser light scattering pattern of dispersed sample. |
| Related Substances | HPLC-UV | Identifies and quantifies structurally related impurities (e.g., Fmoc-deprotected species, diastereomers) using gradient HPLC-UV. |
| Loss on Drying | Thermogravimetric Analysis | Determines volatile content by measuring mass loss upon heating under controlled temperature and airflow (105 C, 2 h). |
| Microbial Contamination | Membrane Filtration | Detects aerobic microorganisms by filtering sample through sterile membrane, culturing on TSA, and enumerating colony-forming units. |
Technical Specifications of FMOC-D-THR-OH
| Test Item | Specification |
|---|---|
| Appearance | White solid |
| Purity | >=98.0% (LC-MS) |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Optical Rotation | +14.0 to +17.0 deg (c=1, in DMF) |
| Melting Point | 145 to 149 °C |
| Identification (NMR) | Consistent with structure |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of FMOC-D-THR-OH
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of FMOC-D-THR-OH
Packaging of FMOC-D-THR-OH
Industrial FMOC-D-THR-OH Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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