China Factory Direct
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| CAS number | 15761-39-4 |
| Product name | BOC-L-Proline |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Pharmaceutical GradeIndustrial GradeSpecialty Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
Based on current marketvolatility and material availability.
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Intermediate for synthesizing peptide-based drugs | Used as a chiral-protected amino acid to incorporate L-proline residues in solid-phase or solution-phase peptide synthesis |
| Biochemical Research | Protein structure and function studies | Applied in constructing peptides with defined sequences to investigate the role of proline in secondary structures (e.g., β-turns) |
| Pharmaceutical R&D | Development of antitumor and antiviral agents | Employed in structural modification and optimization of active candidate compounds to enhance metabolic stability |
| Organic Synthesis | Construction of complex natural product molecules | Utilized as a building block in total synthesis for forming cyclic structures or enabling stereoselective reactions |
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantification based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at 210 nm. |
| Enantiomeric Purity | Chiral HPLC | Separation of L- and D-enantiomers on a chiral stationary phase, with quantification via UV absorbance. |
| Loss on Drying | Gravimetric (105 C, 2 h) | Mass loss measured after drying under controlled temperature and time to determine volatile content including moisture. |
| Residue on Ignition | Gravimetric (Ashing at 600 C) | Measurement of non-volatile inorganic residue remaining after high-temperature combustion. |
| Heavy Metals (as Pb) | ICP-OES | Multi-element quantification of trace metals by plasma excitation and optical emission spectroscopy. |
| Chloride Content | Potentiometric Titration with AgNO3 | Titration with silver nitrate using a silver indicator electrode; endpoint detected by potential change due to AgCl precipitation. |
| Sulfate Content | Turbidimetric Method | Formation of barium sulfate precipitate in acidic medium; quantified by measuring light scattering intensity. |
| Specific Optical Rotation | Polarimetry | Measurement of rotation angle of plane-polarized light induced by chiral molecules in solution at specified concentration and path length. |
| pH (1% aqueous solution) | pH Meter | Electrochemical measurement of hydrogen ion activity in a standardized aqueous solution. |
| Related Substances | HPLC-UV | Detection and quantification of structurally similar impurities using gradient reversed-phase HPLC with UV detection. |
| Water Content | Karl Fischer Titration | Volumetric or coulometric titration based on iodine consumption in a reaction specific to water. |
| Microbial Limits | Membrane Filtration and Plate Count | Enumeration of aerobic microorganisms by filtration, membrane transfer to culture media, and colony counting after incubation. |
| Test Item | Specification |
|---|---|
| Appearance | White crystalline solid |
| Purity | >=98.5% (HPLC), >=98.0% ee |
| Water Content (KF) | <=0.5% |
| Melting Point | 78-82°C |
| Optical Rotation | -62.0 to -58.0° (c=1, in 1M HCl) |
| Total Impurities | <=1.5% |
| Single Impurity | <=0.5% |
| Residue on Ignition | <=0.1% |
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| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.