4-(Trifluoromethyl)nicotinic acid Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 158063-66-2 |
| Product name | 4-(Trifluoromethyl)nicotinic acid |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag500KG/bag1000KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-(Trifluoromethyl)nicotinic acid
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-(Trifluoromethyl)nicotinic acid Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-(Trifluoromethyl)nicotinic acid
| Industry | Application | Process |
|---|---|---|
| Pharmaceuticals | Key intermediate for anti-tuberculosis drugs (e.g., pretomanid) | Organic synthesis |
| Agrochemicals | Synthetic precursor for pyridine-based herbicides (e.g., trifloxysulfuron) | Chemical synthesis |
| Pharmaceuticals | Building block for anticancer and antiviral drug molecules | Drug development |
Manufacturing Quality Control of 4-(Trifluoromethyl)nicotinic acid
| Test Item | Common Test Methods | Method Summary |
|---|---|---|
| Appearance | Visual Inspection | Visually inspect the sample's color, physical form, and crystallization state to determine if it meets the appearance requirements specified in the standard. |
| Purity (Content) | High-Performance Liquid Chromatography (HPLC) | Separate the target compound using a reversed-phase chromatographic column and quantitatively analyze the main component content via a UV detector, commonly using internal or external standard methods. |
| Related Substances (Impurities) | HPLC (Gradient Elution) | Use a gradient elution program to separate the main peak from impurity peaks, and calculate the relative percentage of each impurity based on peak area to assess purity. |
| Water Content | Karl Fischer Titration | Quantitatively react Karl Fischer reagent with water in the sample, and determine the water content through potentiometric titration. |
| Residual Solvents | Gas Chromatography (GC) | Use headspace or direct injection, separate using a capillary column, and quantify residual organic solvents with an FID or ECD detector. |
| Melting Point | Capillary Melting Point Method | Pack the sample into a melting point tube and heat it to observe the initial and final melting temperatures, to assess compound purity and crystal form consistency. |
| pH Value (Solution) | pH Meter Measurement | Prepare an aqueous solution of a certain concentration and measure its acidity or alkalinity using a calibrated pH meter to reflect the characteristics of acidic functional groups. |
| Heavy Metals | Atomic Absorption Spectroscopy (AAS) or ICP-MS | After sample digestion, detect total amounts of heavy metals such as lead, cadmium, mercury, and arsenic using atomic absorption or mass spectrometry. |
| Residue on Ignition | Gravimetric Analysis | Weigh the residue after high-temperature ignition of the sample to evaluate the content of inorganic impurities or ash. |
| Specific Optical Rotation (if applicable) | Polarimetry | If the molecule contains a chiral center, specific optical rotation is measured to control optical purity (Note: 4-Trifluoromethylnicotinic acid typically has no chirality). |
Technical Specifications of 4-(Trifluoromethyl)nicotinic acid
| Test Item | Specification |
|---|---|
| Appearance | Yellow-brown solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 148–152 °C |
| Water Content (KF) | <=0.5% |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Heavy Metals | <=20 ppm |
| Residue on Ignition | <=0.1% |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-(Trifluoromethyl)nicotinic acid
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-(Trifluoromethyl)nicotinic acid
Safety Information of 4-(Trifluoromethyl)nicotinic acid
| Pictograms |  |
| Signal Word | Warning |
| Safety Data Sheet | |
Packaging of 4-(Trifluoromethyl)nicotinic acid
Industrial 4-(Trifluoromethyl)nicotinic acid Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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