4-Methyl-5-bromoimidazole Bulk Supply for Industrial Use
China Factory Direct
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| CAS number | 15813-08-8 |
| Product name | 4-Methyl-5-bromoimidazole |
| Stock | Stock readily available; annual supply capacity exceeding 1,000 tons. |
| Grade | Industrial Grade |
| Packaging | 25KG/bag |
| Sample | Test Samples Available (Click to Request Samples) |
| COA | View COA |
| Price | Get Quote |
| Supply Type | Bulk / Contract manufacturing / OEM |
| Shipping | FCL / LCL available |
| Payment Terms | Support FOB \ CIF \ EXW quotations, and accept Letter of Credit (L/C). |
| Manufacturer | Greenrock Chemical(China Factory) |
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Documents We Provide for 4-Methyl-5-bromoimidazole
Post-sale: Full documentation is provided.
To request documents, please contact us via email at sales@GRchemical.com.
Bulk 4-Methyl-5-bromoimidazole Supplier from China
17+ years in chemical exports.Fully compliant, reliable supply.Your B2B partner in bulk chemical procurement.
Industrial Applications of 4-Methyl-5-bromoimidazole
| Industry | Application | Process |
|---|---|---|
| Pharmaceutical Chemicals | Key intermediate for synthesizing proton pump inhibitors (e.g., omeprazole, pantoprazole, lansoprazole, rabeprazole) | Serves as a critical structural unit to construct the benzimidazole core of drug molecules via coupling or functional group modification reactions |
| Pharmaceutical Chemicals | Intermediate for synthesizing antiparasitic and antifungal agents | Used in nucleophilic substitution or cyclization reactions to build imidazole-containing active pharmaceutical ingredients |
| Agrochemicals | Intermediate for synthesizing high-efficacy, low-toxicity fungicides and insecticides | Acts as a heterocyclic intermediate in condensation reactions to produce agrochemical active ingredients |
| Scientific Research | Organic synthesis building block for designing and developing novel heterocyclic compounds | Leverages bromine atom reactivity in cross-coupling reactions, including Suzuki and Buchwald–Hartwig couplings |
Manufacturing Quality Control of 4-Methyl-5-bromoimidazole
| Detection Item | Common Analytical Method | Method Overview |
|---|---|---|
| Assay (Purity) | HPLC-UV | Quantitative determination based on peak area comparison against a certified reference standard using reversed-phase chromatography and UV detection at ~220 nm. |
| Related Substances | HPLC-UV | Separation and quantification of structurally similar impurities (e.g., 4-methylimidazole, bromination by-products) using gradient HPLC with UV detection. |
| Residual Solvents | GC-FID | Headspace GC with flame ionization detection to quantify low-boiling solvents (e.g., methanol, dichloromethane, toluene) per ICH Q3C guidelines. |
| Water Content | Karl Fischer Titration (Coulometric) | Electrochemical titration measuring water via iodine generation and stoichiometric reaction with water in anhydrous methanol-based medium. |
| Heavy Metals | ICP-MS | Multi-element trace metal quantification (e.g., Pb, Cd, Ni, Fe) after acid digestion, offering sub-ppt detection limits and compliance with ICH Q3D. |
| Residue on Ignition | Gravimetric Analysis (Weight Loss on Ignition) | Measurement of non-volatile inorganic residue after controlled high-temperature ashing (700–800 °C) in a platinum crucible. |
| Melting Point | Capillary Melting Point Apparatus | Thermal transition determination by observing solid-to-liquid phase change under controlled heating rate (e.g., 1 °C/min), used for identity and purity verification. |
| Chloride Impurity | Ion Chromatography (IC) with Conductivity Detection | Separation and quantification of chloride ions (from residual HCl or chlorinated impurities) using anion-exchange column and suppressed conductivity detection. |
| Appearance & Color | Visual Inspection / Hazen Color Scale | Subjective assessment of crystalline form and color intensity against standardized platinum-cobalt solutions (e.g., ≤50 Hazen units). |
Technical Specifications of 4-Methyl-5-bromoimidazole
| Test Item | Specification |
|---|---|
| Appearance | Off-white solid |
| Purity | >=98.0% (HPLC) |
| Melting Point | 142-146°C |
| Total Impurities | <=2.0% |
| Single Impurity | <=0.5% |
| Water Content (KF) | <=0.5% |
| Heavy Metals | <=20 ppm |
Specifications vary by industry. Reach out to our technical experts for a COA tailored specifically to your application. Email:selse@GRchemical.com
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Download COA of 4-Methyl-5-bromoimidazole
| CAS/Product ID | *Required fields | |
| Lot/Batch Number | *Required fields | |
NMR Spectra of 4-Methyl-5-bromoimidazole
Packaging of 4-Methyl-5-bromoimidazole
Industrial 4-Methyl-5-bromoimidazole Procurement FAQ
1. How do you ensure product quality consistency?
We rely on a mature China-based manufacturing system and implement strict batch control and quality inspection for every shipment. Our production process complies with ISO 9001 standards, and a COA is provided for each batch to ensure consistent and reliable quality.
2. Do you offer competitive pricing for bulk orders?
Yes, as a China-based manufacturer and bulk supplier, we provide tiered pricing based on order volume. We support FOB and CIF quotations, as well as L/C payment terms for large transactions to meet international trade requirements.
3. Can you support large-volume or long-term supply?
We have stable production capacity and a well-established supply chain, enabling continuous bulk supply. We support ton-level and container-level orders, as well as long-term cooperation projects.
4. What is your typical lead time?
For in-stock products, shipment can be arranged within 1–3 days. For bulk packaging or customized orders, lead time depends on the specific quantity and production schedule.
5. What documents do you provide?
We can provide complete documentation upon request, including COA, SDS, TDS, and other compliance certificates, meeting industrial procurement and export requirements.
6. Can you customize product specifications or packaging?
Yes, we support customization of parameters such as purity, impurities, residual solvents, and heavy metals. We also offer various bulk packaging options, including 25kg bags, drums, and IBC tanks, suitable for industrial applications and transportation.
7. What shipping options do you support?
We support both FCL (Full Container Load) and LCL (Less than Container Load) shipments, and can flexibly arrange logistics solutions based on order size to meet bulk chemical export needs.
8. Do you provide technical or application support?
Yes, we provide basic application guidance and technical support based on industry experience to help customers optimize product usage.
9. How do you handle compliance and export regulations?
We are familiar with international trade and export regulations, ensuring all products comply with relevant requirements. We also provide complete documentation to support smooth customs clearance and global delivery.
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